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Title Fragment-based drug discovery and x-ray crystallography / volume editors, Thomas G. Davies, Marko Hyvonen ; with contributions by E. Arnold [and others].
Imprint Berlin : Springer, 2012.

LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
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LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
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Series Topics in current chemistry, 1436-5049 ; 317
Topics in current chemistry ; 317.
Subject Drug development.
X-ray crystallography.
Drug Discovery.
Crystallography, X-Ray.
Drug Design.
Alt Name Davies, Thomas G. (Thomas Glanmor)
Hyvönen, Marko.
Arnold, Eddy.
Description 1 online resource (xi, 225 pages) : illustrations (some color).
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Contents Introduction to Fragment-Based Drug Discovery / Daniel A. Erlanson -- Fragment Screening Using X-Ray Crystallography / Thomas G. Davies, Ian J. Tickle -- Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening / Stephen Roughley, Lisa Wright, Paul Brough -- Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors / Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton -- Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery / Michael Hennig, Armin Ruf, Walter Huber -- Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery / Eugene Valkov, Tim Sharpe, May Marsh -- Fragment Screening and HIV Therapeutics / Joseph D. Bauman, Disha Patel, Eddy Arnold -- Fragment-Based Approaches and Computer-Aided Drug Discovery / Didier Rognan.
Summary D.A. Erlanson Introduction to Fragment-Based Drug Discovery T.G. Davies Ian J. Tickle Fragment Screening Using X-Ray Crystallography S. Roughley L. Wright P. Brough A. Massey R.E. Hubbard Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening D.F. Wyss Y.-S. Wang H.L. Eaton C. Strickland J.s H. Voigt Z. Zhu A.W. Stamford Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors M. Hennig A. Ruf Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery E. Valkov T. Sharpe M. Marsh Sa. Greive M. Hyvonen Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery J.h D. Bauman D. Patel E. Arnold Fragment Screening and HIV Therapeutics D. Rognan Fragment-Based Approaches and Computer-Aided Drug Discovery.
Note Online resource; title from PDF title page (SpringerLink, viewed Jan. 30, 2012).
ISBN 9783642275401 (electronic bk.)
3642275400 (electronic bk.)
9783642275395 (print)
3642275397 (print)
ISBN/ISSN 10.1007/978-3-642-27540-1
Publisher # Best.-Nr.: 80017915
OCLC # 774264447
Additional Format Print version: Fragment-based drug discovery and X-ray crystallography. Heidelberg : Springer, 2012 9783642275395 (DLC) 2011945781 (OCoLC)767567954


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