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Title Human herpesviruses / edited by Yasushi Kawaguchi, Yasuko Mori, Hiroshi Kimura.
Imprint Singapore : Springer, [2018]

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Series Advances in experimental medicine and biology, 2214-8019 ; 1045
Advances in experimental medicine and biology ; 1045. 0065-2598
Subject Herpesviruses.
Herpesviridae -- physiology.
Virus Assembly -- physiology.
Herpesviridae Infections -- physiopathology.
Alt Name Kawaguchi, Yasushi,
Mori, Yasuko (Virologist),
Kimura, Hiroshi (Virologist),
Description 1 online resource (viii, 501 pages) : illustrations (chiefly color).
Bibliography Note Includes bibliographical references.
Contents Alphaherpesviruses. The role of HSV glycoproteins in mediating cell entry / Jun Arii, Yasushi Kawaguchi -- Virus assembly and egress of HSV / Colin Crump -- Us3 protein kinase encoded by HSV: the precise function and mechanism on viral life cycle / Akihisa Kato, Yasushi Kawaguchi -- Oncolytic virotherapy by HSV / Daisuke Watanabe, Fumi Goshima -- Neurological disorders associated with human alphaherpesviruses / Jun-ichi Kawada -- Antiviral drugs against alphaherpesvirus / Kimiyasu Shiraki -- Vaccine development for varicella-zoster virus / Tomohiko Sadaoka, Yasuko Mori -- Betaherpesviruses. Glycoproteins of HHV-6A and HHV-6B / Huamin Tang, Yasuko Mori -- Betaherpesvirus virion assembly and egress / William L. Close, Ashley N. Anderson, Philip E. Pellett -- Chromosomal integration by human herpesviruses 6A and 6B / Louis Flamand -- Structural aspects of betaherpesvirus-encoded proteins / Mitsuhiro Nishimura, Yasuko Mori -- Betaherpesvirus complications and management during hematopoietic stem cell transplantation / Tetsushi Yoshikawa -- Vaccine development for cytomegalovirus / Naoki Inoue, Mao Abe, Ryo Kobayashi, Souichi Yamada -- Gammaherpesviruses. KSHV genome replication and maintenance in latency / Keiji Ueda -- Signal transduction pathways associated with KSHV-related tumors / Tadashi Watanabe, Atsuko Sugimoto, Kohei Hosokawa, Masahiro Fujimuro -- Pathological features of Kaposi's sarcoma-associated herpesvirus infection / Harutaka Katano -- EBV-encoded latent genes / Teru Kanda -- Encyclopedia of EBV-encoded lytic genes: an update / Takayuki Murata -- Animal models of human gammaherpesvirus infections / Shigeyoshi Fujiwara -- Gastritis-infection-cancer sequence of Epstein-Barr virus-associated gastric cancer / Masashi Fukayama, Akiko Kunita, Atsushi Kaneda -- EBV in T-/NK-cell tumorigenesis / Hiroshi Kimura -- Vaccine development for Epstein-Barr Virus / Jeffrey I. Cohen.
Summary This book introduces and reviews several topics for each human herpesvirus. One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection and reactivate in later life. Nine human herpesviruses are known so far, and each of them causes a variety of diseases in both primary infection and reactivation. Since the discovery of each human herpesvirus, an abundance of findings related to them has accumulated in basic research and clinical medicine. However, the vast majority of biological features is still masked in mystery. Furthermore, a strategy of treatment and prevention has not yet been established for most human herpesviruses. A wide range of readers will be interested in this volume with its treatment of problematic points and latest findings in the field.
ISBN 9789811072307 (electronic bk.)
9811072302 (electronic bk.)
9789811072291 (hardcover ; alk. paper)
9811072299 (hardcover ; alk. paper)
ISBN/ISSN 10.1007/978-981-10-7230-7
OCLC # 1040618389
Additional Format Print version: Human herpesviruses. Singapore : Springer, [2018] 9789811072291 (DLC) 2018941559 (OCoLC)1006461265

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