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Title Advances in twin and sib-pair analysis / edited by Tim D. Spector, Harold Snieder and Alex J. MacGregor.
Imprint London : Greenwich Medical Media ; [Oxford] : Distributed worldwide by Oxford University Press, 2000.

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Subject Medical genetics -- Statistical methods.
Twins -- Research -- Methodology.
Brothers and sisters -- Research -- Methodology.
Genetics, Medical -- methods.
Twin Studies.
Twins -- genetics.
Diseases in Twins -- genetics.
Alt Name Snieder, Harold.
MacGregor, Alex J.
Spector, T. D. (Timothy David)
Description 1 online resource (xv, 266 pages) : illustrations
Bibliography Note Includes bibliographical references and index.
Note Print version record.
Contents 1. The history of twin and sibling-pair studies / Tim D. Spector -- 2. Influence of design on the outcome of twin studies / David P. Strachan -- 3. Sample selection and outcome definition in twin studies: experiences from the Finnish twin cohort study / Jaakko Kaprio, Pia K. Verkasalo and Markku Koskenvuo -- 4. Practical approaches to account for bias and confounding in twin data / Alex J. MacGregor -- 5. The co-twin control study / David L. Duffy -- 6. Generalisability and assumptions of twin studies / Kirsten Ohm Kyvik -- 7. Fetal programming or genes? / David W. Phillips -- 8. Twin and sib-pair studies in developing countries / Xiping Xu, Changzhong Chen and Tianhua Niu / [and others] -- 9. Comparison of analysis of variance and likelihood models of twin data analysis / Joe C. Christian and Christopher J. Williams -- 10. Path analysis of age-related disease traits / Harold Snieder -- 11. Survival analysis methods in twin research / Andrew Pickles -- 12. Gene-environment interaction and twin studies / Nick Martin -- 13. Why 'common environmental effects' are so uncommon in the literature / John L. Hopper -- 14. Using sib-pairs and parent-child trios in association studies / Cathryn M. Lewis -- 15. The concept of genome-wide power and a consideration of its potential use in mapping polygenic traits: the example of sib-pairs / David B. Allison and Myles S. Faith -- 16. The use of twins in quantitative trait locus mapping / Nicholas J. Schork and Xiping Xu -- 17. Multivariate QTL analysis using structural equation modelling: a look at power under simple conditions / Dorret I. Boomsma and Conor V. Dolan -- 18. QTL mapping with sib-pairs: the flexibility of Mx / Michael C. Neale -- 19. Implications of pharmacogenetic polymorphisms for human health / C. Roland Wolf and Gillian Smith.
Note English.
ISBN 051104299X (electronic bk.)
9780511042997 (electronic bk.)
0585259321 (electronic bk.)
9780585259321 (electronic bk.)
1841100048
OCLC # 45733501
Additional Format Print version: Advances in twin and sib-pair analysis. London : Greenwich Medical Media ; [Oxford] : Distributed worldwide by Oxford University Press, 2000 1841100048 (OCoLC)44678127
Table of Contents
 Contributors 
 Preface 
1The history of twin and sibling-pair studies / Tim D. Spector1
2Influence of design on the outcome of twin studies / David P. Strachan11
3Sample selection and outcome definition in twin studies: experiences from the Finnish twin cohort study / Jaakko Kaprio, Pia K. Verkasalo, Markku Koskenvuo23
4Practical approaches to account for bias and confounding in twin data / Alex J. MacGregor35
5The co-twin control study / David L. Duffy53
6Generalisability and assumptions of twin studies / Kirsten Ohm Kyvik67
7Fetal programming or genes? / David W. Phillips79
8Twin and sib-pair studies in developing countries [et al.] / Xiping Xu, Changzhong Chen, Tianhua Niu91
9Comparison of analysis of variance and likelihood models of twin data analysis / Joe C. Christian, Christopher J. Williams103
10Path analysis of age-related disease traits / Harold Snieder119
11Survival analysis methods in twin research / Andrew Pickles131
12Gene-environment interaction and twin studies / Nick Martin143
13Why 'common environmental effects' are so uncommon in the literature / John L. Hopper151
14Using sib-pairs and parent-child trios in association studies / Cathryn M. Lewis167
15The concept of genome-wide power and a consideration of its potential use in mapping polygenic traits: the example of sib-pairs / David B. Allison, Myles S. Faith181
16The use of twins in quantitative trait locus mapping / Nicholas J. Schork, Xiping Xu189
17Multivariate QTL analysis using structural equation modelling: a look at power under simple conditions / Dorret I. Boomsma, Conor V. Dolan203
18QTL mapping with sib-pairs: the flexibility of Mx / Michael C. Neale219
19Implications of pharmacogenetic polymorphisms for human health / C. Roland Wolf, Gillian Smith245
 Index259


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