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Author Wintour, E. Marelyn.
Title Early Life Origins of Health and Disease / edited by E. Marelyn Wintour, Julie A. Owens.
Imprint Boston, MA : and Springer Science+Business Media, 2006.
Dordrecht : Springer, 2006.

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Author Wintour, E. Marelyn.
Series Advances in Experimental Medicine and Biology, 0065-2598 ; 573.
Advances in experimental medicine and biology ; 573. 0065-2598.
Subject Developmental biology.
Human genetics.
Human physiology.
Embryonic and Fetal Development.
Fetal Development.
Embryonic Development.
Disease Susceptibility.
Risk Factors.
Disease -- etiology.
Maternal Exposure.
Alt Name Owens, Julie A.
Description 1 online resource (xviii, 228 pages) : illustrations.
Contents The developmental origins of health and disease: the breadth and importance of the concept / Peter D. Gluckman and Mark A. Hanson -- Developmental origins of cardiovascular disease, type 2 diabetes, and obesity in humans / Caroline H.D. Fall -- Studies of twins: what can they tell us about the developmental origins of adult health and disease? / Ruth Morley, Terence Dwyer, and John B. Carlin -- Prenatal programming of human motor function / Julia B. Pitcher, David J. Henderson-Smart, and Jeffrey S. Robinson.
Adaptive responses of early embryos to their microenvironment and consequences for post-implantation development / Jeremy Thompson, Michelle Lane, and Sarah Robertson -- Modification of epigenetic state through dietary manipulation in the developing mammalian embryo / Nicola Vickaryous and Emma Whitelaw -- Critical experiments to determine if early nutritional influences on epigenetic mechanisms cause metabolic imprinting in humans / Robert A. Waterland -- Manipulation of the maternal diet in rat pregnancy: different approaches to the demonstration of the programming principle / Simon C. Langley-Evans [and others].
Programming hypertension-animal models: causes and mechanisms / Kate M. Denton, Michelle M. Kett, and Miodrag Dodic -- Developmental programming of cardiovascular dysfunction / Lucilla Poston, James A. Armitage, and Paul D. Taylor -- Kidney development and fetal programming / Karen M. Moritz and Luise A. Cullen-McEwen -- Programming of obesity-experimental evidence / Bernhard H. Breier, Stefan O. Krechowec, and Mark H. Vickers -- Perinatal programming of adult metabolic homeostasis: lessons from experimental studies / Kathryn l. Gatford [and others].
Programming effects of excess glucocorticoid exposure in late gestation / Timothy J.M. Moss and Deborah M. Sloboda -- Programming effects of moderate and binge alcohol consumption / Jeff Schwartz and Luke C. Carey -- Vitamin D in pregnancy and offspring health / Marianne Tare, Helena C. Parkington, and Ruth Morley -- The fetal origins of adult mental illness / Laura Bennet and Alistair J. Gunn -- Hypoxia, fetal growth and developmental origins of health and disease / Dino A. Giussani.
Summary Early Life Origins of Health and Disease is a new book which presents and discusses the many factors that may have impact on normal development. In a concise and readable manner, the authors consider both the proven and suggestive evidence that the high prevalence of hypertension, diabetes, obesity and, in some populations, kidney disease, may not be all due to genetics or adult environment alone. There is good evidence that stress and more subtle dietary deficiencies, as well as placental malfunction, may increase the risk that the offspring will develop these problems in later life. Finally, new and emerging evidence for other areas of human health and disease such a motor control and mental health is critically reviewed for the first time. The book is a 'must' for all scientists interested in researching these areas, as there is a critical evaluation of the methodology used and suggestions for the 'optimal' way in which to investigate these phenomena.
Bibliography Note Includes bibliographical references and index.
Note Print version record.
ISBN 0387326324
ISBN/ISSN 10.1007/0-387-32632-4
OCLC # 228150083
Link Springer e-books.
Additional Format Printed edition: 9780387287157.

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