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Title VEGF in development / [edited by] Christiana Ruhrberg.
Imprint Austin, Tex. : Landes Bioscience/ ; New York : Springer Science+Business Media, 2008.

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Series Molecular biology intelligence unit
Molecular biology intelligence unit (Unnumbered)
Subject Neovascularization.
Vascular endothelial growth factors.
Vascular Endothelial Growth Factor A.
Growth and Development.
Biological Science Disciplines.
Physiological Phenomena.
Vascular Endothelial Growth Factors.
Angiogenic Proteins.
Natural Science Disciplines.
Intercellular Signaling Peptides and Proteins.
Phenomena and Processes.
Disciplines and Occupations.
Biological Factors.
Amino Acids, Peptides, and Proteins.
Chemicals and Drugs.
Vascular Endothelial Growth Factor A -- physiology.
Growth and Development -- physiology.
Alt Name Ruhrberg, Christiana.
Description 1 online resource (106 pages) : illustrations (some color).
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Contents The biology of vascular endothelial cell growth factor isoforms / Yin-Shan Ng -- VEGF receptor signalling in vertebrate development / Joaquim Miguel Vieira, Christiana Ruhrberg, and Quenten Schwarz -- VEGF gene regulation / Marcus Fruttiger -- Embryonic vasculogenesis and hematopoietic specification / Lauren C. Goldie, Melissa K. Nix, and Karen K. Hirschi -- Role of VEGF in organogenesis / Jody J. Haigh -- VEGF and endothelial guidance in angiogenic sprouting / Holger Gerhardt -- Vascular and nonvascular roles of VEGF in bone development / Christa Maes and Geert Carmeliet -- VEGF in the nervous system / Jeffrey M. Rosenstein, Janette M. Krum, and Christiana Ruhrberg.
Summary This book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for development and disease in vertebrates. VEGFA controls the proliferation, migration, specialisation and survival of vascular endothelial cells, and it is therefore essential for the establishment of a functional blood vessel circuit. In addition, VEGFA is emerging as a versatile patterning factor for several non-endothelial cell types in vertebrates. Thus, it plays a central role during organ development at multiple levels, including blood vessel growth, vessel-
Note Print version record.
ISBN 9780387786322
0387786317 (Cloth)
9780387786315 (alk. paper)
OCLC # 311507451
Additional Format Print version: VEGF in development. Austin, Tex. : Landes Bioscience/ ; New York : Springer Science+Business Media, 2008 0387786317 9780387786315 (DLC) 2008009257 (OCoLC)212893650

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