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LEADER 00000cam  2200649Ii 4500 
001    990045818 
003    OCoLC 
005    20181101050634.1 
006    m     o  d         
007    cr cnu|||unuuu 
008    170614s2017    sz a    o     001 0 eng d 
019    990707855|a991582649|a996409274|a999502307|a1005785264
       |a1011852697|a1048196306|a1058227634 
020    9783319562100|q(electronic bk.) 
020    331956210X|q(electronic bk.) 
020    |z9783319562087|q(print) 
020    |z3319562088 
024 7  10.1007/978-3-319-56210-0|2doi 
035    (OCoLC)990045818|z(OCoLC)990707855|z(OCoLC)991582649
       |z(OCoLC)996409274|z(OCoLC)999502307|z(OCoLC)1005785264
       |z(OCoLC)1011852697|z(OCoLC)1048196306|z(OCoLC)1058227634 
040    GW5XE|beng|erda|epn|cGW5XE|dN$T|dEBLCP|dYDX|dUAB|dAZU|dUPM
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       |dU3W|dOCLCO|dCAUOI|dKSU|dVT2|dOCLCO|dAU@ 
049    MAIN 
050  4 RC388.5 
072  7 MED|x014000|2bisacsh 
072  7 MED|x022000|2bisacsh 
072  7 MED|x112000|2bisacsh 
072  7 HEA|x039000|2bisacsh 
072  7 MED|x045000|2bisacsh 
072  7 MJN|2bicssc 
082 04 616.8/1042|223 
245 00 Stroke genetics /|cPankaj Sharma, James F. Meschia, 
       editors. 
250    Second edition. 
264  1 Cham, Switzerland :|bSpringer,|c2017. 
300    1 online resource (xii, 431 pages) :|billustrations (some 
       color) 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
340    |gpolychrome|2rdacc|0http://rdaregistry.info/termList/
       RDAColourContent/1003 
347    text file|2rdaft|0http://rdaregistry.info/termList/
       fileType/1002 
500    Includes index. 
504    Includes bibliographical references at the end of each 
       chapters and index. 
505 0  Introduction -- Familial stroke epidemiology -- 
       Association study results -- GWAS -- Aneurysms/carvernous/
       AVM -- ICH/amyloid/microbleeds -- CADASIL -- Fabry -- 
       MELAS -- Sickle -- Other monogenic -- White matter disease
       -- Carotid atherosclerosis -- Dissection -- 
       Pharmacogenomics -- Non-Caucasian stroke genetics -- Small
       vessel disease -- Genetics of neuroimaging in stroke -- 
       Cerebrovenous thrombosis -- Ethics. 
520    This revised, expanded second edition updates the reader 
       on this fast moving field as well providing an overall 
       understanding of the genetics of complex diseases by using
       stroke as a paradigm. The reader will gain a comprehensive
       understanding of cerebrovascular genetics including the 
       epidemiological evidence for the genetic basis of ischemic
       and hemorrhagic stroke, knowledge of its molecular basis 
       from association, linkage and recent genomewide studies, 
       and also monogenic disorders. Finally, the legal and 
       ethical complexities in dealing with these issues are 
       discussed. Stroke Genetics is a valuable resource for 
       neurologists, stroke physicians, hypertension specialists,
       internists, clinical pharmacologists and those in training,
       as well as researchers in the field of disease genetics. 
588 0  Online resource; title from PDF title page (SpringerLink, 
       viewed June 14, 2017). 
650  0 Cerebrovascular disease|0http://id.loc.gov/authorities/
       subjects/sh85022123|xGenetic aspects.|0http://id.loc.gov/
       authorities/subjects/sh00005917 
650  2 Stroke|xgenetics.|0https://id.nlm.nih.gov/mesh/
       D020521Q000235 
650 14 Medicine & Public Health. 
650 24 Neurology. 
650 24 Internal Medicine. 
650 24 Human Genetics. 
655  4 Electronic books. 
700 1  Sharma, Pankaj|c(Neurologist),|0http://id.loc.gov/
       authorities/names/n2011183764|eeditor. 
700 1  Meschia, James F.,|0http://id.loc.gov/authorities/names/
       n2012189635|eeditor. 
776 08 |iPrint version:|tStroke genetics.|bSecond edition.|dCham,
       Switzerland : Springer, 2017|z3319562088|z9783319562087
       |w(OCoLC)973909154 
990    SpringerLink|bSpringer English/International eBooks 2017 -
       Full Set|c2018-10-31|yNew collection 
       springerlink.ebooks2017|5OH1 
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