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LEADER 00000cam  2200673Mi 4500 
001    855853719 
003    OCoLC 
005    20181023052630.6 
006    m     o  d         
007    cr |n||||||||| 
008    130812s2013    enka    ob    001 0 eng d 
019    865332550|a879653099 
020    0857093681|q(electronic bk.) 
020    9780857093684|q(electronic bk.) 
020    |z9781845698102|q(print) 
020    |z184569810X|q(print) 
035    (OCoLC)855853719|z(OCoLC)865332550|z(OCoLC)879653099 
037    CL0500000428|bSafari Books Online 
040    YDXCP|beng|epn|erda|cYDXCP|dE7B|dN$T|dOPELS|dUMI|dOCLCQ
049    MAIN 
050  4 TP248.2|b.C43 2013 
060  4 QT 37 
060  4 2013 E-759 
072  7 SCI|x013060|2bisacsh 
072  7 TEC|x009010|2bisacsh 
082 04 660.6|223 
245 00 Characterization of biomaterials /|cedited by M. Jaffe, W.
       Hammond, P. Tolias and T. Arinzeh. 
264  1 Oxford :|bWoodhead Publishing,|c2013. 
300    1 online resource (xvi, 318 pages) :|billustrations. 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
347    text file|2rdaft|0
490 1  Woodhead Publishing series in biomaterials,|x2049-9485 ;
       |vnumber 64 
504    Includes bibliographical references and index. 
505 0  Cover; Characterization of biomaterials; Copyright; 
       Contents; Contributor contact details; Woodhead Publishing
       Series in Biomaterials; 1 Microscopy techniques for 
       analyzing the phase nature and morphology of biomaterials;
       1.1 Introduction: basic imaging concepts; 1.2 Image 
       perception and interpretation; 1.3 Light microscopy; 1.4 
       Laser scanning confocal microscopy (LSCM); 1.5 Scanning 
       electron microscopy (SEM); 1.6 Atomic force microscopy 
       (AFM); 1.7 References; 2 Scattering techniques for 
       structural analysis of biomaterials; 2.1 Introduction; 2.2
       Light scattering. 
505 8  2.3 Wide-angle X-ray diffraction2.4 Measuring orientation 
       using X-ray diffraction; 2.5 Small-angle scattering 
       techniques; 2.6 Small-angle X-ray scattering (SAXS); 2.7 
       Small-angle neutron scattering (SANS); 2.8 Acknowledgment;
       2.9 References; 3 Quantitative assays for measuring cell 
       adhesion and motility in biomaterials; 3.1 Introduction; 
       3.2 Cell attachment assays; 3.3 Cell adhesion strength; 
       3.4 Collective motility of cell populations; 3.5 
       Individual cell motility; 3.6 Conclusion and future 
       trends; 3.7 References; 4 Assays for determining cell 
       differentiation in biomaterials. 
505 8  4.1 Introduction4.2 Deoxyribonucleic acid (DNA) and 
       ribonucleic acid (RNA) assays; 4.3 Protein and chemical 
       assays; 4.4 Imaging assays; 4.5 Future trends; 4.6 
       References; 5 Bioreactors for evaluating cell infiltration
       and tissue formation in biomaterials; 5.1 Introduction; 
       5.2 Bioreactor designs; 5.3 Evaluation of cell 
       infiltration and cell seeding; 5.4 Evaluation of tissue 
       formation; 5.5 Importance of computational fluid mechanics
       in modeling, imaging, and simulation of the bioreactors; 
       5.6 Failure of bioreactors; 5.7 Future trends; 5.8 
505 8  5.9 Sources of further information and advice5.10 
       References; 6 Studying molecular-scale protein-surface 
       interactions in biomaterials; 6.1 Introduction: surface-
       induced thrombosis on artificial surfaces; 6.2 Process and
       changes during protein adsorption; 6.3 Factors affecting 
       protein adsorption; 6.4 Models of protein adsorption and 
       adsorption isotherms; 6.5 Protein adsorption kinetics; 6.6
       The Vroman effect; 6.7 Structure and functions of 
       fibrinogen; 6.8 Intermolecular forces and interactions; 
       6.9 Adsorption profile and interfacial kinetics; 6.10 
       Competitive adsorption. 
505 8  6.11 Atomic force microscopy (AFM)6.12 Interfacial 
       properties of fibrinogen studied by AFM; 6.13 Future 
       trends; 6.14 Conclusion; 6.15 References; 7 Assessing the 
       mutagenic effects of biomaterials: analyzing the cellular 
       genome and abnormalities; 7 .1 Introduction; 7.2 DNA 
       structure; 7.3 Genetic mutations; 7.4 Cytogenetic 
       mutations; 7.5 Types of mutations that can occur at the 
       chromosomal level; 7.6 Methods of detection of cytogenetic
       mutations; 7.7 Analyzing genomic organization and 
       variations in genomic copy number; 7.8 Copy number 
       variations (CNVs); 7.9 Epigenetic effects on the genome. 
520    Biomaterials and medical devices must be rigorously tested
       in the laboratory before they can be implanted. Testing 
       requires the right analytical techniques. Characterization
       of biomaterials reviews the latest methods for analyzing 
       the structure, properties and behaviour of biomaterials. 
       Beginning with an introduction to microscopy techniques 
       for analyzing the phase nature and morphology of 
       biomaterials, Characterization of biomaterials goes on to 
       discuss scattering techniques for structural analysis, 
       quantitative assays for measuring cell adhesion, motility 
       and differentiation, and the evaluation of cell 
       infiltration and tissue formation using bioreactors. 
       Further topics considered include studying molecular-scale
       protein-surface interactions in biomaterials, analysis of 
       the cellular genome and abnormalities, and the use of 
       microarrays to measure cellular changes induced by 
       biomaterials. Finally, the book concludes by outlining 
       standards and methods for assessing the safety and 
       biocompatibility of biomaterials. With its distinguished 
       editors and international team of expert contributors, 
       Characterization of biomaterials is an authoritative 
       reference tool for all those involved in the development, 
       production and application of biomaterials. Reviews the 
       latest methods for analyzing the structure, properties and
       behaviour of biomaterialsDiscusses scattering techniques 
       for structural analysis, quantitative assays for measuring
       cell adhesion, and motility and differentiationExamines 
       the evaluation of cell infiltration and tissue formation 
       using bioreactors. 
588 0  Print version record. 
650  0 Biotechnology.|0
650 12 Biocompatible Materials.|0
650 12 Materials Testing|xmethods.|0
650 22 Biocompatible Materials|xstandards.|0https:// 
650 22 Prostheses and Implants|xstandards.|0https:// 
655  4 Electronic books. 
700 1  Jaffe, M.|q(Michael),|0
700 1  Hammond, W.|q(Willis),|0
700 1  Tolias, P.|q(Peter),|0
700 1  Arinzeh, T.|q(Treena),|0
776 08 |iPrint version:|z9781845698102|z184569810X 
830  0 Woodhead Publishing series in biomaterials ;|0http://|vno. 64.|x2049-
990    ProQuest Safari|bO'Reilly Safari Learning Platform: 
       Academic edition|c2018-10-22|yNew collection 
View online

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