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Title The chemistry of contrast agents in medical magnetic resonance imaging.
Imprint Hoboken, NJ : John Wiley & Sons Inc., 2013.
Edition Second edition / edited by Lothar Helm, Andre E. Merbach, Eva Toth.

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Subject Contrast-enhanced magnetic resonance imaging.
Magnetic resonance imaging.
Alt Name Helm, Lothar,
Merbach, Andre E.,
Toth, Eva,
Description 1 online resource
Edition Second edition / edited by Lothar Helm, Andre E. Merbach, Eva Toth.
Summary "The second edition of The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging is a comprehensive treaty covering all aspects of production, use, operating mechanism and theory of these diagnostic agents used to produce high contrast images in MRI. It has been completed to now include recent developments on "classical" Gd-based and iron-oxide probes and chapters dedicated to the most significant advances in molecular imaging probes. Chemical Exchange Saturation Transfer is discussed, which is a novel means of generating MRI contrast"-- Provided by publisher.
"This treatise covers all aspects of production, use, operating mechanism and theory of these diagnostic agents used to produce high contrast images in MRI"-- Provided by publisher.
Bibliography Note Includes bibliographical references and index.
Note Print version record and CIP data provided by publisher.
Contents Cover; Title Page; Copyright; Contents; List of Contributors; Preface; Chapter 1 General Principles of MRI; 1.1 Introduction; 1.2 Theoretical basis of NMR; 1.2.1 Short description of NMR; 1.2.2 Relaxation times; 1.2.3 Saturation transfer; 1.2.4 Concept of localization by magnetic field gradients; 1.3 Principles of magnetic resonance imaging; 1.3.1 Spatial encoding; 1.4 MRI pulse sequences; 1.4.1 Definition; 1.4.2 k-Space trajectory; 1.4.3 Basic pulse sequences.
1.5 Basic image contrast: Tissue characterization without injection of contrast agents (main contrast of an MRI sequence: Proton density (P), T_1 and T_2, T_2̂*)1.5.1 Proton density weighting; 1.5.2 T1 weighting; 1.5.3 T2 weighting; 1.5.4 T2* weighting; 1.6 Main contrast agents; 1.6.1 Gadolinium (Gd) complex agents; 1.6.2 Iron oxide (IO) agents; 1.6.3 CEST agents; 1.7 Examples of specialized MRI pulse sequences for angiography (MRA); 1.7.1 Time of flight angiography: No contrast agent; 1.7.2 Angiography using intravascular contrast agent (Blood pool CA) injection; 1.7.3 DSC DCE MRI.
3.4.4 Ligands with HOPO coordinating arms and related groups3.4.5 H4AAZTA and related ligands; 3.5 Bifunctional ligands and their conjugations; 3.6 Synthesis and characterization of the Ln(III) complexes; 3.6.1 General synthetic remarks; 3.6.2 Characterization of the complexes; List of Abbreviations; References; Chapter 4 Stability and Toxicity of Contrast Agents; 4.1 Introduction; 4.2 Equilibrium calculations.
ISBN 9781118503669 (Adobe PDF)
111850366X (Adobe PDF)
9781118503676 (ePub)
1118503678 (ePub)
9781118503683 (MobiPocket)
1118503686 (MobiPocket)
9781118503652 (electronic bk.)
1118503651 (electronic bk.)
9781119991762 (hardback)
1119991765 (hbk.)
9781299242630
1299242634
OCLC # 820665779
Additional Format Print version: Chemistry of contrast agents in medical magnetic resonance imaging. Second edition / edited by Lothar Helm, Andre E. Merbach, Eva Toth. Hoboken, NJ : John Wiley & Sons Inc., 2013 9781119991762 (DLC) 2012037031



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