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Title Handbook of antimicrobial resistance / Matthias Gotte, editor-in-chief ; Albert Berghuis, Greg Matlashewski, Mark A. Wainberg, Donald Sheppard, editors.
Imprint New York, NY : Springer, [2017]

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Subject Drug resistance in microorganisms -- Handbooks, manuals, etc.
Anti-infective agents -- Handbooks, manuals, etc.
Drug Resistance, Microbial.
Anti-Infective Agents.
Alt Name Götte, Matthias,
Berghuis, Albert,
Matlashewski, Greg,
Wainberg, Mark A.,
Sheppard, Donald,
Description 1 online resource (xvii, 606 pages) : illustrations (some color), color portrait
Bibliography Note Includes bibliographical references and index.
Summary "This is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution"--Publisher's description.
Note Online resource; title from electronic title page (SpringerLink, viewed April 17, 2018).
Contents Bacteria -- Origins of antibiotic resistance (Resistome) -- Dissemination of antibiotic resistance -- Mechanisms of antibiotic resistance.-Strategies for combating antibiotic resistance -- Multiple-drug-resistant bacteria -- Resistant Tuberculosis -- MRSA -- Fungi -- Microevolution of drug resistance -- Environmental induction of azole resistance in medical molds -- Echinocandin resistance in medically relevant fungi -- Role of drug efflux in azole resistance -- Parasites -- Drug-resistant Leishmania -- Drug resistance in Helminth infections -- Drug resistance in Malaria -- Drug resistance in schistosome infections -- Drug resistance in trypanosome infections -- HIV -- Resistance to RT inhibitors -- Resistance to Integrase Inhibitors -- Resistance to Entry inhibitors -- Resistance Testing -- Virology -- Resistance to viral protease inhibitors: The substrate envelope -- Resistance to new Direct-Acting-Antivirals against HCV -- HBV Resistance -- Resistance to antiherpetic drugs -- Influenza Resistance.
Virology. HBV therapy and the problem of drug resistance / A.J. Thompson, S.A. Locarnini -- Protease inhibitor resistance / Johannes Vermehren, Christoph Welsch, Christoph Sarrazin -- Contribution of APOBEC3-driven mutagenesis to HIV evolution and HIV drug resistance / Marsha Dillon-White, Viviana Simon -- Resistance to cyclophilin inhibitors / Philippe Gallay -- Antiviral drug resistance in herpesviruses / Jocelyne Piret, Emilien Drouot, Guy Boivin -- Quasispecies and drug resistance / Celia Perales, Ana M. Ortega-Prieto, Nathan M. Beach, Julie Sheldon, Luis Menendez-Arias, Esteban Domingo -- Substrate-envelope-guided design of drugs with a high barrier to the evolution of resistance / Aysegul Ozen, Celia A. Schiffer -- Bacteriology. The mechanisms of resistance to β-lactam antibiotics / Dustin T. King, Solmaz Sobhanifar, Natalie C.J. Strynadka -- Antibiotic resistance and tolerance in bacterial biofilms / Geoffrey McKay, Dao Nguyen -- Strategies for circumventing bacterial resistance mechanisms / Jed F. Fisher, Jarrod W. Johnson, Shahriar Mobashery -- Drug-resistant tuberculosis / Faiz Ahmad Khan, Greg Fox, Dick Menzies -- Parasitology. The biochemistry of quinoline antimalarial drug resistance / Paul S. Callaghan, Paul D. Roepe -- Drug resistance in Leishmania / Danielle Legare, Marc Ouellette -- Mycology. Microevolution of antifungal drug resistance / Leah E. Cowen -- The role of biofilm matrix in mediating antifungal resistance / Jeniel E. Nett, David Andes -- Mycology. Use of novel tools to probe drug resistance in fungi / Yanan Zhao, David S. Perlin -- Azole resistance in Aspergillus fumigatus: mechanisms, route of resistance selection, and clinical implications / Seyedmojtaba Seyedmousavi, Paul E. Verweij -- The ins and outs of azole antifungal drug resistance: molecular mechanisms of transport / Martin Zavrel, Brooke D. Esquivel, Theodore C. White -- HIV. Transmission of HIV-1 drug resistance / Laura Marije Hofstra, Jean-Claude Schmit, Annemarie M.J. Wensing -- HIV-1 drug resistance in pre-exposure prophylaxis trials / Teri Liegler, Robert Grant -- HIV-1 entry inhibitor resistance / Victor G. Kramer, Mark A. Wainberg -- HIV-1 resistance to reverse transcriptase inhibitors / Grant Schauer, Nicolas Sluis-Cremer -- HIV drug resistance in mothers and infants following use of antiretrovirals to prevent mother-to-child transmission / Scott Olson, Quy Ton, Lisa Frenkel -- HIV protease inhibitor resistance / Annemarie M.J. Wensing, Axel Fun, Monique Nijhuis.
ISBN 9781493906949 (electronic book)
1493906941 (electronic book)
9781493906956 (print and electronic bundle)
149390695X (print and electronic bundle)
9781493906932 (hardcover ; alk. paper)
149390695X (hardcover ; alk. paper)
ISBN/ISSN 10.1007/978-1-4939-0694-9
OCLC # 980301474
Additional Format Print version: Handbook of antimicrobial resistance. New York, NY : Springer, 2017 9781493906956 (DLC) 2016955954 (OCoLC)879603545.

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