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Author He, Rongqiao,
Title Formaldehyde and cognition / Rongqiao He.
Imprint Dordrecht, the Netherlands : Springer, [2017]

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Subject Formaldehyde -- Effectiveness.
Description 1 online resource
Bibliography Note Includes bibliographical references and index.
Contents ""Preface""; ""References""; ""Contents""; ""Chapter 1: Formaldehyde fromA Environment""; ""1 Introduction""; ""2 Formaldehyde Sources""; ""2.1 Natural Sources ofA Formaldehyde""; ""2.2 Anthropogenic Sources ofA Formaldehyde""; ""3 Formaldehyde Inhalation Exposure""; ""3.1 Indoor FormaldehydeA Inhalation Exposure""; ""3.1.1 Indoor Residential Formaldehyde Exposure""; ""3.1.2 Indoor Office Exposure""; ""3.1.3 Indoor Public Exposure""; ""3.1.4 Indoor Occupational Exposure""; ""3.2 Outdoor Air Exposure""; ""4 Dietary Exposure ofA Formaldehyde""; ""5 Formaldehyde Exposure andA Health Problems""
""5.1 Acute Toxicosis""""5.2 Impairment andA Symptoms of Intoxication""; ""6 Formaldehyde inA Biological Evolution andA Metabolism""; ""6.1 The Role ofA Formaldehyde inA Biological Evolution""; ""6.2 The Metabolism ofA Formaldehyde""; ""7 Conclusion""; ""References""; ""Chapter 2: Metabolism ofA Formaldehyde InA Vivo""; ""1 Introduction""; ""2 Endogenous Formaldehyde Generation""; ""2.1 From Environment""; ""2.2 From Food""; ""2.3 Formaldehyde inA One-Carbon Circle""; ""2.4 Formaldehyde fromA Biochemical Compounds""; ""2.4.1 From Protein Denaturation""; ""2.4.2 From Lipid Oxidation""
""2.4.3 From Reducing Sugar Decomposition""""2.4.4 Formaldehyde fromA Dimethylaminoethanol, Dimethylglycine, andA Sarcosine (N-Methylglycine)""; ""2.4.5 From Substrates Containing theA CH3N or CH3O Group Mediated byA Cytochrome P-450 System""; ""2.5 Oxidative Stress Produces Formaldehyde""; ""2.5.1 SSAO Catalyzes Methylamine toA Generate Formaldehyde""; ""2.5.2 Formaldehyde fromA Glycine Oxidation by MPO""; ""2.5.3 Cells Produce Reactive Oxygen Species (ROS) inA theA Presence ofA Formaldehyde andA Vice Versa""; ""2.6 From Intestinal Flora""; ""2.7 From Oxidative Demethylation""
""3 Formaldehyde Metabolic Pathways""""3.1 Mitochondrial ALDH2 Pathway""; ""3.2 Glutathione (GSH)-Dependent Pathway""; ""3.3 Intestinal Microbiota""; ""3.4 Synthesis ofA THF""; ""3.5 Reaction withA Biomacromolecules Such asA Protein, DNA, andA RNA""; ""3.5.1 The Reaction Between Formaldehyde andA Proteins""; ""3.5.2 The Reaction Between Formaldehyde andA Nucleic Acids""; ""3.5.3 The Cross-Links ofA Proteins andA Nucleic Acids Induced byA Formaldehyde""; ""4 Conclusion""; ""References""; ""Chapter 3: Formaldehyde Playing aA Role in (De)methylation forA Memory""; ""1 Introduction""
""2 Formaldehyde Plays aA Role inA DNA Methylation andA Demethylation""""3 Formaldehyde andA RNA Methylation/Demethylation""; ""4 Formaldehyde Is Also Active inA Histone Methylation/Demethylation""; ""5 Methylation andA Demethylation andA Memory""; ""6 Formaldehyde Acting asA anA Epigenetic Factor inA Formation andA Loss ofA Memory""; ""7 Conclusion""; ""References""; ""Chapter 4: Dehydration, Formaldehyde, andA Age-Related Cognitive Impairment""; ""1 Introduction""; ""2 A Progressive Dehydration asA Aging""; ""3 Diminished Thirst Sensation asA Aging""
Summary This book introduces important, new knowledge regarding formaldehyde, especially endogenous formaldehyde, revealing its many key roles in the human body. It reviews the relationship between endogenous formaldehyde and cognition as well as age-related cognitive impairment, by discussing different aspects such as formaldehyde metabolism, its function in the brain, links with epigenetics and neurophysiology, and epidemiological and clinical investigations. The author also provides suggestions on how to prevent cognitive impairment resulting from excess endogenous formaldehyde. This book appeals to all readers who are interested in cognitive science and toxicology.
Note Online resource; title from PDF title page (Ebsco, viewed October 26, 2017).
ISBN 9789402411775 (electronic bk.)
9402411771 (electronic bk.)
ISBN/ISSN 10.1007/978-94-024-1177-5
OCLC # 1007520965
Additional Format Print version: He, Rongqiao. Formaldehyde and cognition. Dordrecht, the Netherlands : Springer, [2017] 9789402411751 9402411755 (OCoLC)992747221