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Title The biochemistry of retinoid signaling. III, Vitamin A and retinoic acid in embryonic development / Mary Ann Asson-Batres, Cecile Rochette-Egly, editors.
Imprint Cham : Springer, 2020.

LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
View online
Series Subcellular Biochemistry ; v.95.
Sub-cellular biochemistry ; v. 95.
Subject Retinoids.
Cellular signal transduction.
Alt Name Asson-Batres, Mary Ann.
Rochette-Egly, Cécile.
Add Title Vitamin A and retinoic acid in embryonic development
LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
View online
Series Subcellular Biochemistry ; v.95.
Sub-cellular biochemistry ; v. 95.
Subject Retinoids.
Cellular signal transduction.
Alt Name Asson-Batres, Mary Ann.
Rochette-Egly, Cécile.
Add Title Vitamin A and retinoic acid in embryonic development
Description 1 online resource (232 pages).
Note Description based upon print version of record.
History
Includes index.
Contents Intro -- Preface -- Contents -- 1 How Dietary Deficiency Studies Have Illuminated the Many Roles of Vitamin A During Development and Postnatal Life -- Introduction -- History -- In Pursuit of an Unknown Factor -- First Impressions of Effects on Postnatal Animals -- Effects of Vitamin A on the Postnatal Nervous System -- Effects of Vitamin A on Reproduction and Embryonic Development -- Development of the Field -- Search for a Mechanism of Action -- Current State of the Field -- Post 1987 -- Vitamin A Deficiency in Postnatal Animals -- Custom Diets
Vitamin A Deficiency Effects on the Rodent Olfactory System -- The Hippocampus-Synaptic Plasticity -- The Cardiovascular System -- Effects of Vitamin A Deficiency on Other Postnatal Systems -- Relevance -- Future Directions -- How Much Vitamin A Do Animals Need for Optimal Health and Longevity? -- Have All Actions of Vitamin A Been Described? -- References -- 2 Maternal-Fetal Transfer of Vitamin A and Its Impact on Mammalian Embryonic Development -- Introduction -- History -- Early Discoveries: VA and Infertility -- Maternal Dietary VA Intake and Fetal Retinoid Concentrations
Maternal VA Status and Fetal Retinoid Concentrations -- Placental VA Levels Versus Fetal Retinoid Concentrations -- Development of the Field -- Maternal-Fetal Transfer of VA: Is There a Role for the RBP-Retinol Complex? -- Maternal-Fetal Transfer of VA: The Role for Other Placental Proteins -- Maternal-Fetal Transfer of Other Retinoids -- Maternal-Fetal Transfer of VA-Unanswered Questions -- Current State of the Field -- The Retinol-RBP Pathway Is the Primary Contributor to Embryonic Development -- Mechanisms of Maternal-Fetal Transfer of VA-Containing Lipoprotein
Other NGS-Based Technologies to Detect Regions Containing RAR Binding Sites -- Integrative Approaches -- Relevance -- Future Directions -- References -- 4 RA Signaling in Limb Development and Regeneration in Different Species -- Introduction -- History -- Development of the Field -- Zebrafish Fin Development -- Amphibian Limb Development -- Amphibian Limb Regeneration -- Chick Limb Development -- Mouse Limb Development -- Current State of the Field -- Complexities of Limb Formation -- Relevance -- The Future -- References -- 5 Retinoic Acid Signaling and Heart Development -- Introduction
Summary This book covers subjects that have major impacts on society, such as the mechanism of maternal-fetal transfer of vitamin A, and the effects of alcohol on retinoic acid signaling and mammalian embryonic development. There has been an awareness of the importance of consuming vitamins throughout human history, but empirical studies of their physiological role and mode of action only began about 150 years ago. Since then, the biochemical nature of vitamin A and its active derivative, retinoic acid, have been identified and researchers around the globe have investigated retinoic acid's physiological function in growth processes and in maintaining life Written by leading experts, this book discusses the latest findings and advances in retinoic acid research. It addresses topics such as the role of retinoic acid signaling in a multitude of processes, including limb, heart and respiratory system development, as well as its role in maintaining postnatal organ systems. This book is a valuable resource for scientists involved in vitamin A/retinoic acid research and readers interested in developmental biology.
ISBN 9783030422820 (electronic bk.)
3030422828 (electronic bk.)
9783030422806 (print)
ISBN/ISSN 10.1007/978-3-030-42282-0
OCLC # 1151190696
Additional Format Print version: Asson-Batres, Mary Ann The Biochemistry of Retinoid Signaling III : Vitamin a and Retinoic Acid in Embryonic Development Cham : Springer,c2020 9783030422806.


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