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Title Naturally occurring antibodies (NAbs) / edited by Hans U. Lutz.
Imprint New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, 2012.

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LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
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Series Advances in experimental medicine and biology ; v. 750
Advances in experimental medicine and biology ; v. 750.
Subject Immunoglobulins.
Autoantibodies.
Antibodies -- immunology.
Alt Name Lutz, Hans U., 1942-
Description 1 online resource (xxi, 267 pages) : illustrations.
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Contents Naturally occurring IgM antibodies to oxidation-specific epitopes / Christoph J. Binder -- Naturally occurring autoantibodies to apoptotic cells / Keith B. Elkon and Gregg J. Silverman -- Naturally occurring antibodies directed against carbohydrate tumor antigens / Reinhard Schwartz-Albiez -- Naturally occurring antibodies as therapeutics for neurologic disease : can human monoclonal IgMs replace the limited resource IVIG? / Arthur E. Warrington [and others] -- Nature and nurture of catalytic antibodies / Sudhir Paul [and others] -- Naturally occurring autoantibodies in mediating clearance of senescent red blood cells / Hans U. Lutz -- Naturally occurring autoantibodies against ss-amyloid / Jan-Philipp Bach and Richard Dodel -- Multi-faceted role of naturally occurring autoantibodies in fighting pathogens / Hicham Bouhlal and Srini Kaveri -- Immunoregulation by naturally occurring and disease-associated autoantibodies : binding to cytokines and their role in regulation of T-cell responses / Claus H. Nielsen and Klaus Bendtzen -- Modulation of dendritic cells and regulatory T cells by naturally occurring antibodies / Jaap Kwekkeboom -- Control of B cells expressing naturally occurring autoantibodies / Jean Louis Pasquali and Thierry Martin -- Granulocyte death regulation by naturally occurring autoantibodies / Stephan Von Gunten and Hans-Uwe Simon -- Naturally occurring autoantibodies mediate ischemia/reperfusion-induced tissue injury / Sherry D. Fleming -- How immune complexes from certain IgG NAbs and any F(ab')2 can mediate excessive complement activation / Hans U. Lutz -- The natural autoantibody repertoire in newborns and adults : a current overview / Asaf Madi [and others] -- Antibody polyspecificity : what does it matter? / Jordan D. Dimitrov, Anastas D. Pashov, Tchavdar L. Vassilev -- Positive and negative selection of natural autoreactive B cells / Richard R. Hardy and Kyoko Hayakawa -- Naturally occurring antibodies/autoantibodies in polyclonal immunoglobulin concentrates / Peter J. Spath and Hans U. Lutz.
Summary This volume illustrates the functional properties of NAbs. Authors from pioneering groups report in their chapters on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. Scientists interested in the regulation and modulation of components of the immune system found a whole variety of NAbs to cytokines with regulatory and protective functions and NAbs that modulate, e.g., dendritic cells, regulatory T cells, B cells and granulocytes. Considering the large plasma pools and initial difficulties in preparing IVIG that does not induce adverse effects upon infusion into recipients, this volume ends with a historical chapter on how pooled human plasma was fractionated and the IgG component pretreated for a safe intravenous application.
Note Print version record.
ISBN 9781461434610 (electronic bk.)
1461434610 (electronic bk.)
9781461434603
1461434602
ISBN/ISSN 9786613925640
OCLC # 807742675
Additional Format Print version: Naturally occurring antibodies (NAbs). New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, 2012 9781461434603 (DLC) 2012005554 (OCoLC)775417066


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