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EBOOK
Title Role of capsaicin in oxidative stress and cancer / Sanjay K. Srivastava, editor.
Imprint Dordrecht : Springer, 2013.

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LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
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Series Diet and cancer ; 3
Diet and cancer (Series) ; 3.
Subject Cancer -- Nutritional aspects.
Capsaicin -- Physiological effect.
Capsaicin -- physiology.
Neoplasms.
Nutritional Physiological Phenomena.
Alt Name Srivastava, Sanjay K.
Description 1 online resource (ix, 178 pages) : illustrations (some color).
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Contents Role of Capsaicin in Cancer Prevention -- Role of Death Receptors Belonging to the TNF Family in Capsaicin-Induced Apoptosis of Tumor Cells -- Role of Capsaicin in Prostate Cancer -- Capsaicin and the Urinary Bladder -- Inhibition of Pancreatitis and Carcinogenesis by Capsaicin -- Cytochrome P450-Dependent Modification of Capsaicinoids: Pharmacological Inactivation and Bioactivation Mechanisms -- The Cancer-Suppressing and -Promoting Actions of Capsaicin -- Oxidative Stress by Capsaicin in Cancer.
Summary This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival p.
ISBN 9789400763173 (electronic bk.)
9400763174 (electronic bk.)
9400763166
9789400763166
9789400763166
OCLC # 841922846
Additional Format Print version: Role of capsaicin in oxidative stress and cancer. Dordrecht : Springer, 2013 (DLC) 2013936405


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