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LEADER 00000nam  22005534i 4500 
001    71797995 
003    OCoLC 
005    20090715153053.0 
006    m        d f       
007    cr cn||||||||| 
008    040403s2004    dcua    sb   f000 0 eng   
040    NLM|beng|erda|cNLM|dOCLCG|dGPO|dMvI 
042    pcc 
060 10 QV 84 
074    0431-E-04 (online) 
086 0  TD 4.210:04/4 
086 0  TD 4.210:04/4 
245 04 The formation of ethanol in postmortem tissues :|bfinal 
       report /|cRobert D. Johnson ... [and others]. 
264  1 Washington, DC :|bOffice of Aerospace Medicine, U.S. Dept.
       of Transportation, Federal Aviation Administration,
300    i, 11 pages :|bdigital, PDF file 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
340    |gpolychrome|2rdacc|0
500    Title from PDF title screen (viewed July 15, 2009). 
500    "February 2004." 
500    "DOT/FAA/AM-04/4." 
504    Includes bibliographical references (p. 10-11). 
520 3  During the investigation of aviation accidents, postmortem
       samples obtained from fatal accident victims are submitted
       to the FAA's Civil Aerospace Medical Institute for 
       toxicological analysis. During toxicological evaluations, 
       ethanol analysis is performed on all cases. Many species 
       of bacteria, yeast and fungi have the ability to produce 
       ethanol and other volatile organic compounds in postmortem
       specimens. The potential for postmortem ethanol formation 
       complicates the interpretation of ethanol-positive results
       from accident victims. Therefore, the prevention of 
       ethanol formation at all steps following specimen 
       collection is a priority. 
520 3  Sodium fluoride is the most commonly used preservative for
       postmortem specimens. Thus, we frequently rely on tissue 
       specimens for ethanol analysis. The postmortem tissue 
       specimens received by our laboratory have generally been 
       subjected to severe trauma and may have been exposed to 
       numerous microbial species capable of ethanol production. 
       With this in mind, we designed an experiment utilizing 
       unadulterated tissue specimens obtained from aviation 
       accident victims to determine the effectiveness of sodium 
       fluoride at various storage temperatures for the 
       prevention of microbial ethanol formation. 
530    Issued also in print. 
536    Performed by FAA Civil Aerospace Medical Institute under 
       task no.|gAM-B-02-TOX-204. 
538    Mode of access: Internet from the FAA web site. Address as
       of 7/15/09:
       oamtechreports/2000s/media/0404.pdf ; current access 
       available via PURL. 
650  0 Alcohol in the body.|0
650  0 Forensic toxicology.|0
650 12 Ethanol|xmetabolism.|0
650 22 Accidents, Aviation.|0 
650 22 Candida albicans|xmetabolism.|0
650 22 Postmortem Changes.|0 
650 22 Sodium Fluoride|xtherapeutic use.|0
700 1  Johnson, Robert D.|q(Robert David) 
710 1  United States.|bOffice of Aerospace Medicine.|0http:// 
776 0  |tformation of ethanol in postmortem tissues|h11 p.
856 40 |u 

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