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Title HPV and cancer / James A. Radosevich, editor.
Imprint Dordrecht ; New York : Springer, 2012.

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Subject Papillomaviruses.
Cancer -- Immunological aspects.
DNA Viruses.
Biological Science Disciplines.
Natural Science Disciplines.
Disciplines and Occupations.
Neoplasms -- immunology.
Alt Name Radosevich, James A. (James Andrew)
Description 1 online resource
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Summary "HPV and Cancer" is a concise read that covers all aspects of the Human Papilloma Virus as it relates to human cancers. While written by professionals, it design to be understandable by those that are not in the field, yet it has the technical details that professionals want to stay abreast of this changing field. The book starts out the history of HPV and progresses into the molecular biology of the virus and our current understand of the structure and functions of the proteins and genes it encodes. We then look at the dynamic trends of this infectious agent in the human population, how it in.
Contents HPV and Cancer; Contents; Human Papillomavirus: A Brief Overview; 1 Introduction; 2 Classification of HPV; 3 The genotype of HPV related to different cancers and diseases; 3.1 Alpha-type papillomavirus; 3.2 Beta-type papillomavirus; 3.3 Gamma, Mu and Nu types; 4 General structure of HPV; 4.1 Genome; 4.2 Capsids Structure; 5 Conclusions; References; Proteins Encoded by the Human Papillomavirus Genome and Their Functions; 1 E1 and E2 Proteins; 2 E6 and E7 Proteins; 3 E4 Proteins; 4 E5 Proteins; 5 L1 and L2 Proteins; 6 Conclusions; References; The Life Cycle of Human Papillomavirus.
1 Introduction2 Infection; 3 Genome Maintenance and Cell Proliferation; 4 Genome Amplification; 5 Virus Assembly and Release; 6 Integration and Tumor Progression; 7 Conclusion; References; Poly-Microbial Interaction with Human Papilloma Virus Leading to Increased Risk for Head and Neck Squamous Cell Carcinoma and Oral Squamous Cell Carcinomas; 1 Poly-Microbial Relationships with Human Papilloma Virus; 2 Poly-Microbial Characteristics and Relationship to Oral Cavity and Pharynx; 3 Poly-Microbial Distribution in Oropharynx and Hypopharynx Tissues.
4 Poly-Microbial Presence Leading to Mucosa Change5 Sites of Microbe Proliferation: Oropharynx and Hypopharynx Tissue and Host Response; 6 Microbial and HPV Invasion Through Mucosa; 7 Streptococci sp. and HPV Capacities for Mucosa Changes; 8 HPV Entry into Keratinocytes; 9 HPV Internalization and Initial Transformation Activity; 10 Microbial Infection and Attachment to HPV/HOK 16B Cells; 11 Microbial Epideminology Associated with Risk for OSCC; 12 Differences Between HPV Associated HNSCC and OSCC; 13 Other Evidence that Microbes Facilitate Cancer Induction: Use of HSGPs.
14 Metabolism of Ethyl Alcohol and Release of Acetaldehyde15 Molecular Changes in Keratinocytes Associated with Bacterial and HPV Infection; References; Patterns and Trends in HPV-Related Oral Cancer and Other HPV-Associated Cancers; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; 4.1 Observations from the Data; 4.2 Detection of HPV/Oral HPV; 5 Conclusions; References; Benign Diseases Associated with Human Papillomavirus Infection; 1 Introduction; 2 Benign HPV Conditions Of Skin; 2.1 Butcher s Wart; 2.1.1 Clinical Features; 2.1.2 Diagnosis; 2.1.3 Treatment and Prognosis.
2.2 Cystic Wart (Plantar Epidermoid Inclusion Cyst)2.2.1 Clinical Features; 2.2.2 Diagnosis; 2.2.3 Treatment and Prognosis; 2.3 Filiform Wart; 2.3.1 Clinical Features; 2.3.2 Diagnosis; 2.3.3 Treatment and Prognosis; 2.4 Verruca Plana (Flat Wart); 2.4.1 Clinical Features; 2.4.2 Diagnosis; 2.4.3 Treatment and Prognosis; 2.5 Verruca Vulgaris, Including Oral Verruca Vulgaris, Verruca Plantaris, Mosaic Wart, and Periungual Wart; 2.5.1 Clinical Features; 2.5.2 Diagnosis; 2.5.3 Treatment and Prognosis; 3 Benign HPV Conditions of Mucosa and Peri-mucosal Skin; 3.1 Bowenoid Papulosis.
Note English.
ISBN 9789400754379 (electronic bk.)
940075437X (electronic bk.)
ISBN/ISSN 10.1007/978-94-007-5437-9
OCLC # 823241941

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