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Title Streptococcus pneumoniae : molecular biology & mechanisms of disease / editor, Alexander Tomasz.
Imprint Larchmont, NY : Mary Ann Liebert, 2000.

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Subject Streptococcus pneumoniae -- Congresses.
Pneumonia -- Congresses.
Streptococcus pneumoniae -- genetics -- Congresses.
Streptococcus pneumoniae -- pathogenicity -- Congresses.
Drug Resistance, Microbial -- Congresses.
Pneumococcal Infections -- drug therapy -- Congresses.
Pneumococcal Infections -- physiopathology -- Congresses.
Alt Name Tomasz, Alexander.
Description 1 online resource (xxi, 501 pages) : illustrations (some color)
Note Based on a workshop held Sept. 23-29, 1996, in Portugal.
Bibliography Note Includes bibliographical references and index.
Contents Part 1. Introduction -- The enduring pneumococcus : unfinished business and opportunities for the future / Robert Austrian -- Streptococcus pneumoniae : functional anatomy / Alexander Tomasz -- Part 2. Chromosome structure, recombination, and cloning -- Structural organization of the streptococcus pneumoniae chromosome and relatedness of penicillin-sensitive and -resistant strains in type 9v / Anne-Marie Gasc [and others] -- DNA sequence sampling and gene disruption for identification of new antibacterial targets in streptococcus pneumoniae / M. Young [and others] -- Streptococcal competence for genetic transformation : regulation by peptide pheromones / Donald A. Morrison -- Control of recombination rate during transformation of streptococcus pneumoniae : an overview / Isabelle Mortier-Barriere [and others] -- Cloning and expression of pneumococcal genes in streptococcus pneumoniae / Sanford A. Lacks -- Part 3. Capsule, cell wall, and virulence factors -- Pneumococcal polysaccharides : a chemical view / Johannis P. Kamerling -- Capsule genetics in streptococcus pneumoniae and a possible role for transposition in the generation of the type 3 locus / Janet Yother, Melissa J. Caimano, Gail G. Hardy -- Characterization of the capsular polysaccharide biosynthesis locus of streptococcus pneumoniae type 19f / James C. Paton, Judy K. Morona, Renato Morona -- A functional analysis of the streptococcus pneumoniae genes involved in the synthesis of type 1 and type 3 capsular polysaccharides / Ernesto Garcia [and others] -- Pneumococcal lipoteichoic and teichoic acid / Werner Fischer -- The peptidoglycan of streptococcus pneumoniae / Alexander Tomasz, Anatoly Severin -- The pneumococcal cell wall degrading enzymes : a modular design to create new lysins? / Jose Luis Garcia [and others] -- Bacteriophages of streptococcus pneumoniae : a molecular approach / Rubens Lopez, Pedro Garcia, Ana C. Martin -- Lipopolysaccharide and peptidoglycan : cd14-dependent bacterial inducers of inflammation / Hans-Dieter Flad [and others] -- Versatility of choline-binding domain / Rubens Lopez [and others] -- Phase variation in colony opacity by streptococcus pneumoniae / Jeffrey N. Weiser -- Pneumococcal proteins PSPA and PSPC : their potential for use as vaccines / Susan K. Hollingshead [and others] -- Molecular analysis of putative pneumococcal virulence proteins / James C. Paton, Anne M. Berry, Robert A. Lock -- Relationship of structure to function in pneumolysin / Timothy J. Mitchell [and others] -- Biological properties of pneumolysin / Timothy J. Mitchell, Peter W. Andrew -- Calcium signaling in streptococcus pneumoniae : implication of the kinetics of calcium transport / Marie-Claude Trombe -- Part 4. Pneumococcal disease and animal models -- Molecular and cellular biology of pneumococcal infection / Elaine I. Tuomanen, H. Robert Masure -- Opsonic and nonopsonic interactions of C3 with streptococcus pneumoniae / Margaret K. Hostetter -- Pneumococcal meningitis : current pathophysiologic concepts / Merle A. Sande, Martin G. Tauber -- Invasive pneumococcal disease in the immunocompromised host / Edward N. Janoff, Jeffrey B. Rubins -- Otitis media : the chinchilla model / G. Scott Giebink -- Immunization and protection in pneumococcal otitis media studied in a rat model / Karin Prellner [and others] -- Incidence of invasive pneumococcal disease in Denmark / Jorgen Henrichsen, Susanne Vinther Nielsen -- Part 5. Antibiotic resistance -- Serotypes and clones of antibiotic-resistant pneumococci / Alexander Tomasz, Keith P. Klugman, Lesley McGee -- Molecular bases of three characteristic phenotypes of pneumococcus : optochin-sensitivity, coumarin-sensitivity, and quinolone-resistance / Ernesto Garcia [and others] -- Antibiotic resistance in streptococcus pneumoniae in spain : an overview of the 1990s / Josefina Linares, Fe Tubau, M. Angeles Dominguez -- Impact of antibiotic resistance on chemotherapy for pneumococcal infections / Josefina Linares [and others] -- Effect of antimicrobial use and other risk factors on antimicrobial resistance in pneumococci / Karl G. Kristinsson -- Molecular evolution of rifampicin resistance in streptococcus pneumoniae / Christopher G. Dowson, Mark Enright, Piotr Zawadski, Paul Pickerill -- Penicillin-binding proteins in [beta]-lactam-resistant streptococcus pneumoniae / Regine Hakenbeck [and others] -- The molecular mechanisms of tetracycline resistance in the pneumococcus / Keith P. Klugman, Carol A. Widdowson -- Part 6. Surveillance and intervention -- Cem/net : clinical microbiology and molecular biology in alliance / Alexander Tomasz, Herminia de Lencastre, Ilda Santos Sanches -- Penicillin-resistant streptococcus pneumoniae : an international molecular epidemiological study / Marcel Sluijter [and others] -- Pneumococcal disease and the role of conjugate vaccines / David L. Klein -- Epidemiology of pneumococcal serotypes and conjugate vaccine formulations / Jay C. Butler -- Streptococcus pneumoniae : at the threshold of the 21st century / Alexander Tomasz, Robert F. Breiman, Daniel M. Musher.
Note Print version record.
ISBN 0585225621 (electronic bk.)
9780585225623 (electronic bk.)
0913113859
9780913113851
OCLC # 44956624
Additional Format Print version: Streptococcus pneumoniae. Larchmont, NY : Mary Ann Liebert, 2000 0913113859 (DLC) 99043059 (OCoLC)42022644



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