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Title Immunological tolerance : methods and protocols / edited by Paul J. Fairchild.
Imprint Totowa, N.J. : Humana Press, 2007.

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Series Methods in molecular biology ; v. 380.
Methods in molecular biology (Clifton, N.J.) ; v. 380.
Subject Immunological tolerance -- Laboratory manuals.
T-Lymphocytes -- immunology.
Models, Animal.
Dendritic Cells -- immunology.
Clinical Laboratory Techniques.
Immune Tolerance.
Immunosuppression -- Laboratory manuals.
Dendritic cells -- Immunology -- Laboratory manuals.
Alt Name Fairchild, Paul J.
Ohio Library and Information Network.
Description xiv, 477 pages : illustrations (some color) ; 24 cm.
monochrome rdacc
Bibliography Note Includes bibliographical references and index.
Contents Frontiers of immunological tolerance / Giogrgio Raimondi, Heth R. Turnquist, and Angus W. Thomson -- Part I, Cell types contributing to immunological tolerance -- Balancing tolerance and immunity: the role of dendritic cell and t cell subsets / Elena Shklovskaya and Barbara Fazekas de St. Groth -- Differentiation of dendritic cell subsets from mouse bone marrow / Ludovica Bruno -- Genetic modification of dendritic cells through the directed differentiation of embryonic stem cells / Paul J. Fairchild, Kathleen F. Nolan, and Herman Waldmann -- Generation of immunocompetent t cells from embryonic stem cells / Renee F. de Pooter and Juan Carlos Zuniga-Pflucker -- Isolation, expansion, and characterization of human natural and adaptive regulatory t cells / Silvia Gregori [and others] -- Derivation, culture, and characterization of thymic epithelial cell lines / Michiyuki Kasai and Toshiaki Mizuochi -- Part II, The study of immunological tolerance in vitro -- Thymus organogenesis and development of the thymic stroma / Craig S. Nowell, Alison M. Farley, and C. Clare Blackburn -- Generation of a tissue-engineered thymic organoid / Fabrizio Vianello and Mark C. Poznansky -- Studying t-cell repertoire selection using fetal thymus organ cultures / Philip G. Ashton-Rickardt -- Investigating central tolerance with reaggregate thymus organ cultures / Graham Anderson and Eric J. Jenkinson -- Estimating thymic function through quantification of t-cell receptor excision circles / Marie-Lise Dion, Rafick-Pierre Sekaly, and Remi Cheynier -- Gene expression profiling of dendritic cells by microarray / Maria Foti, Paola Ricciardi-Carastagnoli, and Francesca Granucci -- SAGE analysis of cell types involved in tolerance induction / Kathleen F. Nolan, Stephen P. Cobbold, and Herman Waldmann -- Analyzing the physicodynamics of immune cells in a three-dimensional collagen matrix / Peter Reichardt, Frank Gunzer, and Matthias Gunzer -- Part III, The study of immunological tolerance in vivo -- Etiology of autoimmune disease: how t cells escape self-tolerance / Eli Sercarz and Claudia Raja-Gabaglia -- Animal models of spontaneous autoimmune disease: type 1 diabetes in the nonobese diabetic mouse / Nadia Giarratana, Giuseppe Penna, and Luciano Adorini -- Antigen-based therapy and immune regulation in experimental autoimmune encephalomyelitis / Mandy J. McGeachy [and others] -- Induction and regulation of inflammatory bowel disease in immunodeficient mice by distinct CD4+ t-cell subsets / Kevin J. Maloy -- In vivo models for the study of transplantation tolerance / Hanna Stewart, Rommel Ravanan, and Richard Smith -- Ectopic transplantation of tissues under the kidney capsule / Nathan J. Robertson, Paul J. Fairchild, and Herman Waldmann -- Intravital two-photon imaging of t-cell priming and tolerance in the lymph node / Susanna Celli and Philippe Bousso -- Tracing tolerance and immunity in vivo by CFSE-labeling of administered cells / Elizabeth Ingulli -- Part IV, Methods for inducing and breaking immunological tolerance -- Thymic involution: implications for self-tolerance / Frances T. Hakim and Ronald E. Gress -- Inducing mixed chimerism and transplantation tolerance through allogeneic bone marrow transplantation with costimulation blockade / Ines Pree and Thomas Wekerle -- Induction of dominant tolerance using monoclonal antibodies / Ana Agua-Doce and Luis Graca -- Induction of tolerance by adoptive transfer of treg cells / Kanji Nagahama, Eiji Nishimura, and Shimon Sakaguchi -- Modulation of the immune response using dendritic cell-derived exosomes / Nicole R. Bianco [and others] -- Breaking self-tolerance to tumor-associated antigens by in vivo manipulation of dendritic cells / Ines Mende and Edgar G. Engleman.
Access Available to OhioLINK libraries
Summary Immunological Tolerance: Methods and Protocols is a comprehensive guide to the techniques currently used for culturing and characterising the cell types responsible for imposing self-tolerance and the experimental models employed to study their function both in vitro and in vivo.
Reproduction Electronic resource. Berlin : Springer, 2008.
System Details Mode of access: World Wide Web
ISBN 1588296520 (alk. paper)
1597453951 (ebook)
9781588296528 (alk. paper)
9781597453950 (ebook)
OCLC # 232302373
Link OhioLINK electronic book center (OCoLC)180989150.
SpringerLink (OCoLC)43927870.
Additional Format Print version: Immunological tolerance. Totowa, N.J. : Humana Press, 2007 1588296520 9781588296528 (DLC) 2006024123 (OCoLC)70713511.

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