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Title Brain hypoxia and ischemia : with special emphasis on development / Gabriel G. Haddad, Shan Ping Yu, editors.
Imprint New York : Humana Press, 2009.

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Series Contemporary clinical neuroscience
Contemporary clinical neuroscience.
Subject Cerebral anoxia.
Cerebral ischemia.
Brain Diseases.
Cerebrovascular Disorders.
Brain Ischemia.
Hypoxia, Brain.
Central Nervous System Diseases.
Vascular Diseases.
Nervous System Diseases.
Cardiovascular Diseases.
Hypoxia, Brain -- physiopathology.
Brain Ischemia -- physiopathology.
Alt Name Haddad, Gabriel G., 1947-
Yu, Shan Ping.
Description 1 online resource (xi, 343 pages) : illustrations.
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Summary Focuses on the mechanisms of cell injury and cell survival in the brain, with emphasis on development and early life, in relation to hypoxia and ischemia in the brain. This volume addresses a number of research ideas such as: role of mitochondria; role of ROS; role of hypoxia vs ischemia vs insult paradigm; and, cell fate in the penumbra.
Contents Hybernation and CNS survival -- High CO2 and ischemia -- ROS and brain injury in ischemia -- Apoptotic surface delivery of K+ channels -- Intermittent low O2 and brain function -- Mechainsms of injury and survival in hypoxia and ischemia in the CNS -- Regulation of apoptotic volume decrease and apoptosis by plasma membrane aquaporin activity -- Mitochondrial mechanisms in ischemia/hypoxia -- Blood flow and hypoxia/ischemia in CNS -- Mitochondrial permeability transition and cell death -- Neurodegeneration and hypoxia/ischemia -- Glutamate and NO in the CNS -- HIF and brain hypoxia -- Calcium-permeable acid-sensing ion channels in brain ischemia -- Regulation of ion channels and receptors in brain ischemia -- Factors influencing cell death in the penumbra -- Critical roles of Na+, K+-ATPase in apoptosis and CNS diseases -- Mechanisms of tolerance/susceptibility in the CNS -- SIDS and PVL/prematurity and white matter injury.
Note Print version record.
ISBN 9781603275798
1603275789 (cased)
9781603275781 (cased)
OCLC # 314798044
Additional Format Print version: Brain hypoxia and ischemia. New York : Humana Press, 2009 9781603275781 1603275789 (DLC) 2008939850 (OCoLC)310075095

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