Return to home page
Searching: Muskingum library catalog
Some OPAL libraries remain closed or are operating at reduced service levels. Materials from those libraries may not be requestable; requested items may take longer to arrive. Note that pickup procedures may differ between libraries. Please contact your library for new procedures, specific requests, or other assistance.
  Previous Record Previous Item Next Item Next Record
  Reviews, Summaries, etc...
EBOOK
Title Biological small angle scattering : techniques, strategies and tips / Barnali Chaudhuri, Ines G. Munoz, Shuo Qian, Volker S. Urban, editors.
Imprint Singapore : Springer, [2017]
2017

LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
View online
Series Advances in experimental medicine and biology, 2214-8019 ; volume 1009
Advances in experimental medicine and biology ; v. 1009. 2214-8019
Subject Small-angle scattering.
Scattering, Small Angle.
Alt Name Chaudhuri, Barnali Neel,
Muñoz, Inés G.,
Qian, Shuo,
Urban, Volker S.,
LOCATION CALL # STATUS MESSAGE
 OHIOLINK SPRINGER EBOOKS    ONLINE  
View online
Series Advances in experimental medicine and biology, 2214-8019 ; volume 1009
Advances in experimental medicine and biology ; v. 1009. 2214-8019
Subject Small-angle scattering.
Scattering, Small Angle.
Alt Name Chaudhuri, Barnali Neel,
Muñoz, Inés G.,
Qian, Shuo,
Urban, Volker S.,
Description 1 online resource : color illustrations.
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Contents Sample and Buffer preparation for SAXS -- Considerations for sample preparation using size-exclusion chromatography -- How to analyze and present SAS data for publication -- Designing and Performing Biological Solution Small-Angle Neutron Scattering Contrast Variation Experiments on Multi-component Assemblies -- SAS-based structural modeling and model validation -- Structural Characterization of Highly Flexible Proteins by Small-Angle Scattering -- What can we learn from wide-angle solution scattering? -- SAS-based studies of protein fibrillation -- High Resolution Distance Distributions Determined by X-ray and Neutron Scattering -- A successful combination: coupling SE-HPLC with SAXS -- Applications of SANS to study membrane protein systems -- Hybrid applications of solution scattering to aid structural biology -- A practical guide to iSPOT modeling: An integrative structural biology platform -- Small angle scattering for pharmaceutical applications: From drugs to drug delivery system.
Summary This book provides a clear, comprehensible and up-to-date description of how Small Angle Scattering (SAS) can help structural biology researchers. SAS is an efficient technique that offers structural information on how biological macromolecules behave in solution. SAS provides distinct and complementary data for integrative structural biology approaches in combination with other widely used probes, such as X-ray crystallography, Nuclear magnetic resonance, Mass spectrometry and Cryo-electron Microscopy. The development of brilliant synchrotron small-angle X-ray scattering (SAXS) beam lines has increased the number of researchers interested in solution scattering. SAS is especially useful for studying conformational changes in proteins, highly flexible proteins, and intrinsically disordered proteins. Small-angle neutron scattering (SANS) with neutron contrast variation is ideally suited for studying multi-component assemblies as well as membrane proteins that are stabilized in surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatography further increases the range of SAS applications. The book is written by leading experts in solution SAS methodologies. The principles and theoretical background of various SAS techniques are included, along with practical aspects that range from sample preparation to data presentation for publication. Topics covered include techniques for improving data quality and analysis, as well as different scientific applications of SAS. With abundant illustrations and practical tips, we hope the clear explanations of the principles and the reviews on the latest progresses will serve as a guide through all aspects of biological solution SAS. The scope of this book is particularly relevant for structural biology researchers who are new to SAS. Advanced users of the technique will find it helpful for exploring the diversity of solution SAS methods and applications. Chapter 3 of this book is available open access under a CC BY 4.0 license at link.springer.com.
Note Online resource; title from PDF title page (EBSCO, viewed December 14, 2017).
ISBN 9789811060380 (electronic bk.)
981106038X (electronic bk.)
9789811060373
9811060371
OCLC # 1015215344
Additional Format Print version: Biological small angle scattering. Singapore : Springer, [2017] 9811060371 (DLC) 2017956347 (OCoLC)992781811


If you experience difficulty accessing or navigating this content, please contact the OPAL Support Team