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Title Combination vaccines : development, clinical research, and approval / edited by Ronald W. Ellis.
Imprint Totowa, N.J. : Humana Press, 1999.

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Subject Combined vaccines.
Vaccines, Combined.
Alt Name Ellis, Ronald W.
Description 1 online resource (xvi, 279 pages) : illustrations
Bibliography Note Includes bibliographical references and index.
Summary A diverse team of leading experts comprehensively review the complex biology of a wide variety of vaccine combinations, as well as the technical, clinical, and regulatory aspects of their development. Topics covered range from the use of immunological correlates of efficacy, rather than efficacy per se, for the evaluation and licensure of vaccine combinations, to preserving a stable immunogenic mixture in appropriate containers according to accepted regulatory standards. Discussed in detail are the trivalent influenza vaccine, the pneumococcal polysaccharide vaccine, the MMR vaccine, the DTP vaccine and its combinations, and the quadrivalent rotavirus vaccine, all of which serve as models for the development of future combinations. Combination Vaccines: Development, Clinical Research, and Approval illuminates all the scientific, clinical, regulatory, and health care issues involved in the research, development, and human use of combination vaccines.
Access Use copy Restrictions unspecified star
Reproduction Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
System Details Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212
Note digitized 2010 HathiTrust Digital Library committed to preserve pda
Print version record.
Contents 1. Pediatric Combination Vaccines / Emmanuel Vidor, Agnes Hoffenbach and Stanley Plotkin -- 2. Combination Vaccines in Adolescents and Adults / Peter A. Gross -- 3. Pharmaceutical Aspects of Combination Vaccines / Dennis M. Katkocin and Chia-Lung Hsieh -- 4. Pediatric Combination Vaccines: Clinical Issues / Peter R. Paradiso and Robert Kohberger -- 5. Immunological Correlates for Efficacy of Combination Vaccines / Ronald W. Ellis -- 6. Influenza Vaccines / Bert E. Johansson -- 7. Vaccines Against Streptococcus pneumoniae / Kenneth R. Brown and Francis M. Ricci -- 8. Rotavirus Vaccines / Paul A. Offit and H. Fred Clark -- 9. Combined Measles, Mumps, and Rubella Vaccines / Maurice R. Hilleman -- 10. Combination Vaccines: Regulatory Considerations for Developers / John R. Vose -- 11. Testing and Licensure of Combination Vaccines for the Prevention of Infectious Diseases / Lydia A. Falk, Karen Midthun and Loris D. McVittie / [and others] -- 12. Issues for Health Practitioners in the Use of Combination Vaccines / Kathryn M. Edwards and Michael D. Decker.
ISBN 0585262292 (electronic bk.)
9780585262291 (electronic bk.)
9781592592654 (electronic bk.)
1592592651 (electronic bk.)
9781475748024 (print)
1475748027 (print)
0896037177 (alk. paper)
9780896037175 (alk. paper)
ISBN/ISSN 10.1007/978-1-59259-265-4
OCLC # 45729962
Additional Format Print version: Combination vaccines. Totowa, N.J. : Humana Press, 1999 0896037177 (DLC) 98055262 (OCoLC)40555835
Table of Contents
 Preface 
 Contributors 
1Pediatric Combination Vaccines / Emmanuel Vidor, Agnes Hoffenbach, Stanley Plotkin1
2Combination Vaccines in Adolescents and Adults / Peter A. Gross35
3Pharmaceutical Aspects of Combination Vaccines / Dennis M. Katkocin, Chia-Lung Hsieh51
4Pediatric Combination Vaccines: Clinical Issues / Peter R. Paradiso, Robert Kohberger95
5Immunological Correlates for Efficacy of Combination Vaccines / Ronald W. Ellis107
6Influenza Vaccines / Bert E. Johansson155
7Vaccines Against Streptococcus pneumoniae / Kenneth R. Brown, Francis M. Ricci155
8Rotavirus Vaccines / Paul A. Offit, H. Fred Clark171
9Combined Measles, Mumps, and Rubella Vaccines / Maurice R. Hilleman197
10Combination Vaccines: Regulatory Considerations for Developers / John R. Vose213
11Testing and Licensure of Combination Vaccines for the Prevention of Infectious Diseases [et al.] / Lydia A. Falk, Karen Midthun, Loris D. McVittie233
12Issues for Health Practitioners in the Use of Combination Vaccines / Kathryn M. Edwards, Michael D. Decker249
 Index269


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