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EBOOK
Title DNA vaccines : types, advantages, and limitations / Erin C. Donnelly and Arthur M. Dixon, editors.
Imprint New York : Nova Biomedical Books, c2011.

Series Immunology and immune system disorders.
Immunology and immune system disorders.
Subject DNA vaccines.
Vaccines, DNA.
Alt Name Donnelly, Erin C.
Dixon, Arthur M.
Series Immunology and immune system disorders.
Immunology and immune system disorders.
Subject DNA vaccines.
Vaccines, DNA.
Alt Name Donnelly, Erin C.
Dixon, Arthur M.
Description 1 online resource.
Bibliography Note Includes bibliographical references and index.
Note Description based on print version record.
Contents DNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; IMMUNOLOGY AND IMMUNE SYSTEM DISORDERS ; DNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; Contents ; Preface ; Novel Carrier Adjuvant for DNA Vaccination ; Abstract ; 1. Introduction ; 2. Immunology of DNA Vaccines: Mode of Action and Immune Response Induction ; 3. Barriers in DNA Vaccine Delivery and Possible Modes to Overcome these Barriers ; 4. Novel Strategies for DNA Delivery ; 4.1. Lipid Based Carrier Adjuvants for DNA Vaccination ; 4.1.1. Liposomes ; 4.1.2. Virosomes.
4.2. Polymers and Polymeric Carriers Systems 4.2.1. Polyethylenimine ; 4.2.2. Polylysine ; 4.2.3. Chitosan ; 4.2.4. Dendrimers ; 5. Concluding Remark and Future Prospects ; References ; Improving the Immunogenicity of DNA Vaccines: A Nano-Sized Task? ; Abstract ; Introduction ; Improving Immunogenicity of Plasmid DNA Vaccines ; Routes of Delivery of Plasmid DNA Vaccines ; Physical Delivery Systems of Plasmid DNA Vaccines ; Needle-Free Delivery Methods ; Expression Optimization ; Cytokines ; Delivery Vectors for DNA Vaccines ; Bacterial Vectors ; Viral Vectors.
DNA and RNA Replicons Nano-Sized Vehicles for Gene Delivery ; Inorganic to Biomaterial -- Past to Future ; Size Determines the Fate of Particles ; Conclusion ; References ; Novel Delivery Strategies for DNA ; Abstract ; I. Introduction ; II. Optimization of Immunogenicity of DNA Vaccines ; 2.1. Choice of Targets and Expression Plasmid for DNA Vaccines ; 2.2. Selection of High Expression Plasmids for DNA Vaccines ; 2.3. Codon Optimization for Higher Gene Expression ; 2.4. Adjuvant Choice for DNA Vaccines ; III. DNA Delivery Strategies ; 3.1. Invasive Delivery.
3.1.1. Needle Injection 3.1.2. In Vivo Electroporation ; 3.1.3. Tattoo Gun Delivery ; 3.2. Non-Invasive Topical Delivery Method ; 3.2.1. Tape Stripping ; 3.2.2. Nanopatch Delivery ; 3.2.3. Nano-Particle Mediated Delivery ; 3.3. Viral-Mediated DNA Delivery Systems ; 3.4. Non-Viral Gene Delivery Systems ; 3.5. Novel Delivery Methods ; 3.5.1. Laser Mediated Delivery ; 3.5.2. Ultrasound Mediated Delivery System ; III. Future Directions ; References ; Recent Advances in DNA Vaccines ; Abstract ; Introduction ; DNA Vaccines X Traditional Vaccine Approaches ; Components of a DNA Vaccine.
How DNA Vaccines Work Delivery Methods ; Advantages X Limitations ; Strategies to Enhance Immunogenicity of DNA Vaccines ; Modifications of Plasmid Basic Design ; Delivery Methods ; Target to Dendritic Cells ; Improved Immunization Protocols ; Adjuvants ; Conclusion ; References ; Co-Administration of Gamma Interferon Gene with DNA Vaccine Expressing Duck Hepatitis B Virus (DHBV) Proteins Enhances Therapeutic Efficacy of DNA-Based Immunization in Chronic Virus Carriers ; Abstract ; Introduction ; Materials and Methods ; Animals ; DNA Immunization.
ISBN 9781620810453 ebook
162081045X
1613244444 hardcover : alk. paper
9781613244449 hardcover : alk. paper
OCLC # 952772313
Additional Format Print version: DNA vaccines New York : Nova Biomedical Books, c2011. 9781613244449 (hardcover : alk. paper) (DLC) 2011012604.


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