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Title Immunomic discovery of adjuvants and candidate subunit vaccines / edited by Darren R. Flower, Yvonne Perrie.
Imprint New York : Springer, 2013.

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Series Immunomics reviews ; 5
Immunomics reviews ; v. 5.
Subject Vaccines.
Immunological adjuvants.
Vaccines -- Design -- History.
Adjuvants, Immunologic.
Vaccines -- pharmacology.
Vaccines -- history.
Alt Name Flower, Darren R.
Perrie, Yvonne.
Description 1 online resource.
polychrome rdacc
Contents Immunomic Discovery of Adjuvants, Delivery Systems, and Candidate Subunit Vaccines: A Brief Introduction / Darren R. Flower, Yvonne Perrie -- Bacterial Genomes and Vaccine Design / Valeria Cafardi, John L. Telford -- Identification of Candidate Vaccine Antigens In Silico / Darren R. Flower, Matthew N. Davies -- Post-genomic Antigen Discovery: Bioinformatical Approaches to Reveal Novel T Cell Antigens of Mycobacterium bovis / Martin Vordermeier, Gareth J. Jones -- Genome-Based Computational Vaccine Discovery by Reverse Vaccinology / Yongqun He -- Computational Prediction of Protein Subcellular Localization, Genomic Islands, and Virulence to Aid Antigen Discovery / Bhavjinder K. Dhillon, Nancy Y. Yu -- On the Development of Vaccine Antigen Databases: Progress, Opportunity, and Challenge / Hifzur Rahman Ansari, Darren R. Flower -- What Have Dendritic Cells Ever Done for Adjuvant Design? Cellular and Molecular Methods for the Rational Development of Vaccine Adjuvants / Alexander D. Edwards -- Towards the Systematic Discovery of Immunomodulatory Adjuvants / Darren R. Flower -- Designing Liposomes as Vaccine Adjuvants / Malou Henriksen-Lacey, Yvonne Perrie -- Designing Nonionic Surfactant Vesicles for the Delivery of Antigens for Systemic and Alternative Delivery Routes / Jitinder Wilkhu, Anil Vangala -- Immune Stimulating Complexes (ISCOMs) and Quil-A Containing Particulate Formulations as Vaccine Delivery Systems / S. Hook, T. Rades -- Formulation and Characterisation of PLGA Microspheres as Vaccine Adjuvants / Daniel J. Kirby, Randip Kaur, Yvonne Perrie -- Powder Vaccines for Pulmonary Delivery / Tom Jin, Eric Tsao.
Summary Vaccine discovery is one of the most exciting and fast-moving areas of applied science. Since Edward Jenner's work in the 18th century, vaccines have transformed health across the globe. Bringing together clinical, experimental, and computational disciplines vaccinology addresses the most pressing needs of 21st century health-care: the great infectious diseases threatening the developing world, such as HIV, Malaria, and TB; and chronic diseases, such as dementia, threatening the developed world. This volume seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology.
Bibliography Note Includes bibliographical references and index.
Note Print version record.
ISBN 9781461450702 (electronic bk.)
1461450705 (electronic bk.)
1461450691 (hbk.)
9781461450696 (hbk.)
ISBN/ISSN 10.1007/978-1-4614-5070-2
OCLC # 822030021
Additional Format Print version: Immunomic discovery of adjuvants and candidate subunit vaccines. New York ; London : Springer, 2012 9781461450696 (OCoLC)817270611

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