Astroviruses were first identified in the feces of children in 1975. Since then, they have been found in ̃ 3 to 20 per cent of children with diarrhea. Given that serological studies have demonstrated that up to 90 per cent of children have been exposed to at least one strain of astrovirus by age 9, the prevalence of infection may be much higher. Supporting this are studies demonstrating that astroviruses can also be isolated in a subset of asymptomatic individuals, suggesting that a proportion of infected individuals shed the virus asymptomatically or for some time after the resolution of othe.
Includes bibliographical references and index.
Preface -- Epidemiology of Human Astroviruses -- Replication Cycle of Astroviruses -- Astrovirus Structure and Assembly -- Astrovirus Pathogenesis -- Immune Responses -- Astrovirus Taxonomy -- New Human Astroviruses -- Astrovirus Infections in Animal Mammalian Species -- Avian Astroviruses -- Index.
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