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LEADER 00000cam  2200793Ii 4500 
001    535027323 
003    OCoLC 
005    20190303125529.6 
006    m     o  d         
007    cr mn||||||||| 
008    100301s2009    gw a    ob    001 0 eng d 
010    2009929030 
015    GBB023350|2bnb 
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020    9783642021756|q(e-isbn) 
020    3642021751|q(e-isbn) 
020    |z9783642021749 
020    |z3642021743 
024 7  10.1007/978-3-642-02175-6|2doi 
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049    MAIN 
050  4 QR1|b.E62 v.339 
050  4 QR201.A37|bH58 2009eb 
060  4 WC503.3|bH58 2009 
070    QR201.A37|bH57 2009 
072  7 SCI|x045000|2bisacsh 
072  7 MMFM|2bicssc 
072  7 SCI|x008000|2bisacsh 
082 04 579.2|222 
245 00 HIV interactions with host cell proteins /|cPaul Spearman,
       Eric O. Freed, editors. 
264  1 Heidelberg ;|aNew York :|bSpringer,|c2009. 
300    1 online resource (x, 204 pages) :|billustrations (chiefly
       color). 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
340    |gpolychrome|2rdacc|0http://rdaregistry.info/termList/
       RDAColourContent/1003 
347    text file|2rdaft|0http://rdaregistry.info/termList/
       fileType/1002 
490 1  Current topics in microbiology and immunology,|x0070-217X 
       ;|vv. 339. 
504    Includes bibliographical references and index. 
505 0  Host restriction of HIV-1 by APOBEC3 and viral evasion 
       through Vif -- Interactions of viral protein U (Vpu) with 
       cellular factors -- TRIM5alpha -- Human immunodeficiency 
       virus type-1 Gag and host vesicular trafficking pathways -
       - The roles of tetraspanins in HIV-1 replication -- 
       Imaging of HIV/host protein interactions -- Virological 
       and cellular roles of the transcriptional coactivator 
       LEDGF/p75 -- Implications of Nef: host cell interactions 
       in viral persistence and progression to AIDS -- Vpr and 
       its interactions with cellular proteins. 
520    The authors seek to understand the assembly process of 
       human immunodeficiency virus (HIV) and to develop a 
       vaccine that can effectively neutralize HIV. HIV assembly 
       is a process directed by the viral Gag polyprotein. Gag is
       a myristoylated precursor protein that is translated in 
       the cytoplasm and then traffics to the plasma membrane or 
       to endosomal vesicles for assembly. The authors have 
       recently described an interaction between Gag and the 
       delta subunit of the AP-3 adaptor protein complex (1). The
       mechanism and structural basis for this interaction is now
       under intense study. Our hypothesis i. 
546    English. 
588 0  Print version record. 
650  0 HIV infections.|0http://id.loc.gov/authorities/subjects/
       sh91004036 
650  0 Host-virus relationships.|0http://id.loc.gov/authorities/
       subjects/sh85062421 
650  0 Cell receptors.|0http://id.loc.gov/authorities/subjects/
       sh85021665 
650 12 HIV Infections|xvirology.|0https://id.nlm.nih.gov/mesh/
       D015658Q000821 
650 14 Biomedicine. 
650 22 Carrier Proteins.|0https://id.nlm.nih.gov/mesh/D002352 
650 22 Viral Proteins|xmetabolism.|0https://id.nlm.nih.gov/mesh/
       D014764Q000378 
650 24 Virology. 
650 24 Cancer Research. 
655  4 Electronic books. 
700 1  Spearman, Paul.|0http://id.loc.gov/authorities/names/
       nb2010004037 
700 1  Freed, Eric O.|0http://id.loc.gov/authorities/names/
       nb2010004038 
776 08 |iPrint version:|tHIV interactions with host cell 
       proteins.|dHeidelberg ; New York, NY : Springer, 2009
       |z9783642021749|w(DLC)  2009929030|w(OCoLC)401157161. 
830  0 Current topics in microbiology and immunology ;|0http://
       id.loc.gov/authorities/names/n42036058|v339. 
912    .b15411114JOHNC 
990    SpringerLink|bSpringer English/International eBooks 2009 -
       Full Set|c2018-11-23|yMaster record variable field(s) 
       change: 650|5OH1 
990    SpringerLink|bSpringer English/International eBooks 2009 -
       Full Set|c2019-03-02|yMaster record variable field(s) 
       change: 505|5OH1 
990    SpringerLink|bSpringer English/International eBooks 2009 -
       Full Set|c2018-11-30|yMaster record variable field(s) 
       change: 650|5OH1 
990    SpringerLink|bSpringer English/International eBooks 2009 -
       Full Set|c2018-11-16|yMaster record variable field(s) 
       change: 650|5OH1 
990    SpringerLink|bSpringer English/International eBooks 2009 -
       Full Set|c2018-11-02|yMaster record variable field(s) 
       change: 650|5OH1 
990    SpringerLink|bSpringer English/International eBooks 2009 -
       Full Set|c2018-10-31|yNew collection 
       springerlink.ebooks2009|5OH1 
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