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EBOOK
Title Checkpoint controls and cancer / guest editor, M.B. Kastan.
Imprint Plainview, NY : Cold Spring Harbor Laboratory Press, 1997.

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Series Cancer surveys, 0261-2429 ; v. 29
Cancer surveys ; v. 29.
Subject Cancer cells -- Proliferation -- Molecular aspects.
Biological control systems.
Cancer cells -- Growth -- Regulation.
Neoplasms -- genetics.
Molecular Biology.
Cyclin-Dependent Kinases.
Genes, cdc.
Protein p53.
Cell Cycle Proteins.
Alt Name Kastan, M. B. (Michael B.)
Imperial Cancer Research Fund (Great Britain)
Description 1 online resource (vi, 363 pages) : illustrations.
Note "Published for the Imperial Cancer Research Fund."
Bibliography Note Includes bibliographical references and index.
Contents Introduction / Michael B. Kastan -- Control of the g[subscript 1]/s transition / S.I. Reed -- S phase damage sensing checkpoints in mammalian cells / J.M. Larner, H. Lee and J.L. Hamlin -- Cyclins and the g[subscript 2]/m transition / M.R. Jackman and J.N. Pines -- The DNA replication licensing system / Pia Thommes and J. Julian Blow -- Cyclin dependent kinase inhibitors / J. Wade Harper -- Yeast checkpoint controls and relevance to cancer / T. Weinert -- The anaphase promoting complex / A.M. Page and P. Hieter -- Mammalian g[subscript 1] and g[subscript 2] phase checkpoints / P.M. O'Connor -- Maintaining genetic stability through tp53 mediated checkpoint control / G.M. Wahl, S.P. Linke and T.G. Paulson [and others] -- Functions of the DNA dependent protein kinase / Shengfang Jin, Satoshi Inoue and David T. Weaver -- Telomerase, checkpoints and cancer / Calvin B. Harley and Steven W. Sherwood.
Note Print version record.
ISBN 0585317291 (electronic bk.)
9780585317298 (electronic bk.)
0879695188
OCLC # 45728665
Additional Format Print version: Checkpoint controls and cancer. Plainview, NY : Cold Spring Harbor Laboratory Press, 1997 0879695188 (DLC) 97189760 (OCoLC)37183645
Table of Contents
 Introduction / Michael B. Kastan1
 Control of the G[subscript 1]/S Transition / S. I. Reed7
 S Phase Damage Sensing Checkpoints in Mammalian Cells / J. M. Larner, H. Lee, J. L. Hamlin25
 Cyclins and the G[subscript 2]/M Transition / M. R. Jackman, J. N. Pines47
 The DNA Replication Licensing System / Pia Thommes, J. Julian Blow75
 Cyclin Dependent Kinase Inhibitors / J. Wade Harper91
 Yeast Checkpoint Controls and Relevance to Cancer / T. Weinert109
 The Anaphase Promoting Complex / A. M. Page, P. Hieter133
 Mammalian G[subscript 1] and G[subscript 2] Phase Checkpoints / P. M. O'Connor151
 Maintaining Genetic Stability through TP53 Mediated Checkpoint Control / G. M. Wahl, S. P. Linke, T. G. Paulson [et al.]183
 Functions of the DNA Dependent Protein Kinase / Shengfang Jin, Satoshi Inoue, David T. Weaver221
 Telomerase, Checkpoints and Cancer / Calvin B. Harley, Steven W. Sherwood263
 The ATM Gene and Protein: Possible Roles in Genome Surveillance, Checkpoint Controls and Cellular Defence against Oxidative Stress / Galit Rotman, Yosef Shiloh285
 Apoptosis and Cancer Mechanisms / Huichin Pan, Chaoying Yin, Terry Van Dyke305
 Genetic Instability in Animal Tumorigenesis Models / Larry A. Donehower329
 Biographical Notes353
 Index357


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