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Title Evidence-based gastroenterology and hepatology / edited by John W.D. McDonald, Brian G. Feagan, Rajiv Jalan, Peter J. Kahrilas.
Imprint Hoboken, NJ : John Wiley & Sons, Inc., 2019.
Edition Fourth edition.

View online
View online
Series Evidence-Based Medicine Ser.
Evidence-Based Medicine Ser.
Subject Gastroenterology -- Textbooks.
Hepatology -- Textbooks.
Gastrointestinal system -- Diseases -- Textbooks.
Liver -- Diseases -- Textbooks.
Evidence-based medicine -- Textbooks.
Gastrointestinal Diseases -- diagnosis.
Gastrointestinal Diseases -- therapy.
Liver Diseases -- diagnosis.
Liver Diseases -- therapy.
Evidence-Based Medicine -- methods.
Alt Name McDonald, John W. D.,
Feagan, Brian G.,
Jalan, Rajiv, 1962-
Kahrilas, Peter,
Description 1 online resource
Edition Fourth edition.
Bibliography Note Includes bibliographical references and index.
Note Online resource; title from digital title page (viewed on March 12, 2019).
Contents Intro; Evidence-Based Gastroenterology and Hepatology; Dedication; Contents; Contributors; Preface; PART I Gastrointestinal disorders; 1 Gastroesophageal reflux disease; Introduction; Definition of GERD; Clinical presentation; Epidemiology; Pathophysiology; Natural history and complications; Diagnostic tests; Symptom assessment and questionnaires; PPI trial; Upper GI endoscopy; Ambulatory GERD testing: pH and pH-impedance monitoring; Esophageal high-resolution manometry; Barium swallow; Mucosal impedance; Treatment; Lifestyle modifications; Antacids and alginates
Histamine-2 receptor antagonistsProton pump inhibitors; Potassium competitive acid blockers; Reflux inhibitors; Prokinetic drugs; Targeting hypersensitivity; Antireflux surgery; Novel surgical and endoscopic procedures; Conclusion; References; 2 Barretts esophagus; Introduction; Definition; Pathogenesis; Epidemiology; Incidence and prevalence; Risk factors; Natural history; Diagnosis; Endoscopy; Diagnosis-histopathology; Advanced endoscopic imaging in BE; Screening and surveillance; Screening; Surveillance; Treatment; Acid suppression
Chemoprevention of esophageal adenocarcinoma with anti-inflammatory agentsEndoscopic therapies for Barretts esophagus; Conclusion; References; 3 Esophageal motility disorders; Achalasia; Treatment of achalasia; Overview; Pharmacologic treatment; Botulinum toxin; Pneumatic dilation; Heller myotomy; Per-oral endoscopic myotomy (POEM); Comparisons among treatment modalities; Esophagectomy; Summary; Spastic motor disorders; Treatment of spastic motility disorders; Overview; Medications; Botulinum toxin; Pneumatic dilation; Heller myotomy; POEM; Summary; References; 4 Eosinophilic esophagitis
IntroductionSearching for the evidence; Definition; Etiology and pathogenesis; Genetics and genetic variants; Environmental factors; Epidemiology; Diagnosis; General approach and differential diagnosis; GERD and PPI-REE; Features in children; Features in adults; Endoscopic features; Histologic features; Prognosis and natural history; Management; Corticosteroids; Biologics; Leukotriene antagonists and mast cell stabilizers; Immunomodulators; Dietary therapy; Endoscopic management with dilation; Future advances; Evaluation and prognosis; Novel therapies; Summary of treatment data
AcknowledgmentsReferences; 5 Ulcer disease and Helicobacter pylori infection: current treatment; Introduction; What is the evidence for the role of H. pylori in peptic ulcer disease?; Association of H. pylori with ulcer disease (strength, consistency, and specificity); Duodenal ulcer; Duodenal ulcers not related to H. pylori and NSAIDs; Gastric ulcer; Temporal relationship; Biological gradient; Biological plausibility; Effects of interventions: outcomes following H. pylori eradication; Coherence of the data with earlier epidemiological information; Treatment of duodenal ulcer
ISBN 9781119211396 (electronic book)
1119211395 (electronic book)
9781119211402 (electronic book)
1119211409 (electronic book)
9781119211419 (electronic book)
1119211417 (electronic book)
9781119211389 (hardcover)
ISBN/ISSN 16092996
OCLC # 1057238499
Additional Format Print version: Evidence-based gastroenterology and hepatology. Fourth edition. Hoboken, NJ : Wiley-Blackwell, 2019 9781119211389 (DLC) 2018046910

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