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Title Journey from cognition to brain to gene : perspectives from Williams syndrome / [edited by] Ursula Bellugi and Marie St. George.
Imprint Cambridge, Mass. : MIT Press, [2001]

Subject Williams syndrome -- Pathophysiology.
Williams syndrome -- Genetic aspects.
Cognition disorders in children.
Williams Syndrome -- genetics.
Brain -- pathology.
Cognition -- physiology.
Williams Syndrome -- physiopathology.
Williams Syndrome -- psychology.
Alt Name Bellugi, Ursula, 1931-
St. George, Marie.
Description 1 online resource (xx, 189 pages) : illustrations
monochrome rdacc
Bibliography Note Includes bibliographical references and index.
Contents 1. The neurocognitive profile of Williams syndrome : a complex pattern of strengths and weaknesses / by Ursula Bellugi [and others] -- 2. Hypersociability : the social and affective phenotype of Williams syndrome / by Wendy Jones [and others] -- 3. Neurophysiological markers of face processing in Williams syndrome / by Debra L. Mills [and others] -- 4. Neuroanatomy of Williams syndrome : a high-resolution MRI study / by Allan L. Reiss [and others] -- 5. Cellular and molecular cortical neuroanatomy i Williams syndrome / by Albert M. Galaburda and Ursula Bellugi -- 6. Genome structure and cognitive map of Williams syndrome / by Julie R. Korenberg [and others].
Note Print version record.
Summary A blueprint for the investigation of neurodevelopmental disorders, this book presents the work of a team of scientists using a multidisciplinary, integrated approach to link genes with human behavior. Using Williams syndrome as a model, leading researchers in neuroanatomy, neurocognition, neurophysiology, and molecular genetics have built bridges between disciplines to link higher cognitive functions, their underlying neurobiological bases, and their molecular genetic underpinnings. One of the book's many strengths is that the scientists from each discipline studied the same individuals with Williams syndrome. As the book shows, Williams syndrome is a fascinating disorder because of the "peaks and valleys" among cognitive domains: severe intellectual deficits but remarkably spared and effusive language; specific impairment in spatial construction but great strength in face processing and sociability. By capitalizing on these dissociations in higher cognitive functioning, the book provides a model for the study of brain-behavior relationships as well as for the mapping of brain and behavior phenotypes to the genome and beyond. Contributors Ralph Adolphs, Twyla Alvarez, Lawrence Appelbaum, Ursula Bellugi, Dennis Burian, Xiao-Ning Chen, Michael Chiles, Stephan Eliez, Albert Galaburda, Hanao Hirota, Wendy Jones, Julie Korenberg, Zona Lai, Liz Lichtenberger, Alan Lincoln, Rumiko Matsuoka, Debra Mills, Helen Neville, Judy Reilly, Allan Reiss, Bruce Roe, Marie St. George, J. Eric Schmidtt, Erica Straus.
Note English.
ISBN 9780262287395 (electronic bk.)
0262287390 (electronic bk.)
OCLC # 61658083
Additional Format Print version: Journey from cognition to brain to gene. Cambridge, Mass. : MIT Press, ©2001 0262523124 (DLC) 00054892 (OCoLC)45635188.

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