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Title Stroke genetics / Pankaj Sharma, James F. Meschia, editors.
Imprint Cham, Switzerland : Springer, 2017.
Edition Second edition.

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Subject Cerebrovascular disease -- Genetic aspects.
Stroke -- genetics.
Alt Name Sharma, Pankaj (Neurologist),
Meschia, James F.,
Description 1 online resource (xii, 431 pages) : illustrations (some color)
Edition Second edition.
Note Includes index.
Contents Introduction -- Familial stroke epidemiology -- Association study results -- GWAS -- Aneurysms/carvernous/AVM -- ICH/amyloid/microbleeds -- CADASIL -- Fabry -- MELAS -- Sickle -- Other monogenic -- White matter disease -- Carotid atherosclerosis -- Dissection -- Pharmacogenomics -- Non-Caucasian stroke genetics -- Small vessel disease -- Genetics of neuroimaging in stroke -- Cerebrovenous thrombosis -- Ethics.
Summary This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
Bibliography Note Includes bibliographical references at the end of each chapters and index.
Note Online resource; title from PDF title page (SpringerLink, viewed June 14, 2017).
ISBN 9783319562100 (electronic bk.)
331956210X (electronic bk.)
9783319562087 (print)
ISBN/ISSN 10.1007/978-3-319-56210-0
OCLC # 990045818
Additional Format Print version: Stroke genetics. Second edition. Cham, Switzerland : Springer, 2017 3319562088 9783319562087 (OCoLC)973909154

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