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Title An introduction to high content screening : imaging technology, assay development, and data analysis in biology and drug discovery / editors, Steven A. Haney and Doug Bowman ; associate editors, Arijit Chakravarty, Anthony Davies, and Caroline Shamu.
Imprint Hoboken, New Jersey : John Wiley & Sons Inc., [2015]

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Subject Drugs -- Analysis.
Drug development.
Drug Design.
Systems Biology -- methods.
Data Interpretation, Statistical.
Drug Evaluation, Preclinical -- methods.
Image Processing, Computer-Assisted -- methods.
Models, Biological.
Alt Name Haney, Steven A.,
Bowman, Doug, active 2014,
Chakravarty, Arijit,
Davies, Anthony, active 2014,
Shamu, Caroline,
Description 1 online resource
Bibliography Note Includes bibliographical references and index.
Contents Introduction / Steven Haney -- Fluorescence and cell labeling / Anthony Davies, Steven Haney -- Microscopy fundamentals / Steven Haney, Anthony Davies, Doug Bowman -- Image processing / John Bradley, Doug Bowman, Arijit Chakravarty -- Selecting and setting up a high content imaging platform / Craig Furman, Doug Bowman, Anthony Davies, Caroline Shamu, Steven Haney -- Informatics considerations / Jay Copeland, Caroline Shamu -- Basic high content assay development / Steven Haney, Doug Bowman -- Designing metrics for high content assays / Arijit Chakravarty, Steven Haney, Doug Bowman -- Analyzing well-level data / Steven Haney, Arijit Chakravarty -- Analyzing cell level data / Steven Haney, Lin Guey, Arijit Chakravarty -- Designing robust assays / Arijit Chakrivarty, Doug Bowman, Anthony Davies, Caroline Shamu -- Automation and screening / John Donovan, Arijit Chakravarty, Anthony Davies, Steven Haney, Doug Bowman, John Ringling, Ben Knight -- High content analysis for tissue samples / Kristine Burke, Vaishali Sinde, Alice McDonald, Doug Bowman, Arijit Chakrivarty -- Factoring and clustering high content data / Steven Haney, Arijit Chakravarty -- Supervised machine learning / Jeff Palmer, Arijit Chakravarty.
Note Print version record and CIP data provided by publisher.
Summary Using a collaborative and interdisciplinary author base withexperience in the pharmaceutical industry and academia, this book is a practical resource for high content (HC) techniques. Instructs readers on the fundamentals of highcontent screening (HCS) techniques ; Focuses on practical and widely-used techniques likeimage processing and multiparametric assays ; Breaks down HCS into individual modules for trainingand connects them at the end. Includes a tutorial chapter that works through sampleHCS assays, glossary, and detailed appendices.
ISBN 9781118859476 (electronic bk.)
1118859472 (electronic bk.)
0470624566 (cloth)
9780470624562 (cloth)
9780470624562 (cloth)
OCLC # 883749352
Additional Format Print version: Introduction to high content screening. Hoboken, New Jersey : John Wiley & Sons Inc., [2015] 9780470624562 (DLC) 2014025606 (OCoLC)883748714

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