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EBOOK
Title The Mouse in biomedical research. Volume I : History, wild mice, and genetics / edited by James G. Fox [and others].
Imprint Amsterdam ; Boston : Academic Press, [2007]
©2007
Edition Second edition.

Series American College of Laboratory Animal Medicine series.
American College of Laboratory Animal Medicine series.
Subject Mice as laboratory animals.
Animal models in research.
Animals, Laboratory.
Mice.
Biomedical Research.
Disease Models, Animal.
Models, Genetic.
Alt Name Fox, James G.
Add Title History, wild mice, and genetics
Description 1 online resource (1 volume (xvi, 326 pages)) : illustrations (some color).
polychrome rdacc
Edition Second edition.
Bibliography Note Includes bibliographical references and index.
Note Print version record.
Contents Cover -- Copyright page -- Table of Contents -- List of Reviewers for Chapters in this Volume -- List of Contributors -- Foreword for Volume I -- Preface -- Chapter 1: Building a Better Mouse: One Hundred Years of Genetics and Biology -- Chapter 2: Systematics of the Genus Mus -- Chapter 3: The Secret World of Wild Mice -- Chapter 4: Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types -- Chapter 5: Mouse Strain and Genetic Nomenclature: An Abbreviated Guide -- Chapter 6: The Mouse Genome -- Chapter 7: Gene Mapping -- Chapter 8: Genetic Monitoring -- Chapter 9: Cytogenetics -- Chapter 10: Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man -- Chapter 11: Gamete and Embryo Manipulation -- Chapter 12: Chemical Mutagenesis in Mice -- Chapter 13: Gene-Specific Mutagenesis -- Chapter 14: Gene Transfer Studies Using Mouse Models -- Chapter 15: Mouse and Human Pluripotent Stem Cells -- Chapter 16: Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics -- Index.
Summary History, Wild Mice, and Genetics provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.
ISBN 9780080469065 (electronic bk.)
008046906X (electronic bk.)
OCLC # 85857971
Additional Format Print version: Mouse in biomedical research. Volume I. 2nd ed. Amsterdam ; Boston : Academic Press, ©2007 9780123694553 (OCoLC)70178101.


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