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EBOOK
Title New generation vaccines / edited by Myron M. Levine [and others].
Imprint New York : M. Dekker, 1997.
Edition 2nd ed., rev. and expanded.

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Subject Vaccines.
Vaccines.
Alt Name Levine, Myron M. (Myron Max), 1944-
Description 1 online resource (xvi, 1214 pages) : illustrations
Edition 2nd ed., rev. and expanded.
Bibliography Note Includes bibliographical references and index.
Note Print version record.
ISBN 0585340188 (electronic bk.)
9780585340180 (electronic bk.)
0824700619 (hardcover ; alk. paper)
OCLC # 47010008
Additional Format Print version: New generation vaccines. 2nd ed., rev. and expanded. New York : M. Dekker, 1997 0824700619 (DLC) 97012541 (OCoLC)36682381
Table of Contents
 Preface 
 Contributors 
1Vaccines and Vaccination in Historical Perspective / Myron M. Levine, Rosanna Lagos1
2The Traditional Vaccines: An Overview / Gordon L. Ada13
3An Overview of Biotechnology as Applied to Vaccine Development / Graeme C. Woodrow25
4Initial Clinical Evaluation of New Vaccine Candidates: Phase 1 and 2 Clinical Trials of Safety, Immunogenicity, and Preliminary Efficacy / Carol O. Tacket, Tacket J. Mattheis, Margaret Baker Rennels35
5Long-Term Evaluation of Vaccine Protection: Methodological Issues for Phase 3 Trials and Phase 4 Studies / John D. Clemens, Abdollah Naficy, Malla R. Rao47
6Economic Analyses of Vaccines and Vaccination Programs: Evaluating the Economic Rationale for Immunization / Orin S. Levine, Benjamin Schwartz69
7Reaping the Benefits: Getting Vaccines to Those Who Need Them / J. W. Lee, Bruce Aylward, Harry F. Hull [et al.]79
8Progress and Challenges in Modern Vaccinology: An Immunologist's Perspective / Gustav J. V. Nossal89
9The Eradication of Vaccine-Preventable Diseases / William Foege93
10Recent Advances in Immunology: Impact on Vaccine Development / Marcelo B. Sztein, Graham F. Mitchell99
11Computer Prediction of T-Cell Epitopes / Anne S. De Groot, Gabriel E. Meister, James L. Cornette [et al.]127
12Identification of B- and T-Cell Epitopes Through Structural Characterization and Peptide Technology / Juan A. Cooper, Allan J. Saul139
13The Gastrointestinal Mucosal Immune System / Stephen P. James151
14Adjuvants for the Future / Robert Edelman173
15Proteosomes for Improved Nasal, Oral, or Injectable Vaccines / George H. Lowell193
16Liposomes as Adjuvants for Vaccines / Carl R. Alving207
17Prospects for the Development of New and Improved Vaccines Through the Use of Microencapsulation Technology / Derek T. O'Hagan215
18Antigen Cochleate Preparations for Oral and Systemic Vaccination / Raphael J. Mannino, Susan Gould-Fogerite229
19Ty Virus-like Particles as an Antigen Delivery System / Guy T. Layton239
20Immunopotentiating Reconstituted Influenza Virosomal Vaccine Delivery System / Reinhard Gluck, Stanley J. Cryz, Jr.247
21Mutant Pertussis and Escherichia coli Heat-Liable Toxins as Adjuvants for Enhancing Local and Systemic Immune Responses to Coadministered, Nonliving Antigens / Gillian Douce, Gordon Dougan, MariaGrazia Pizza [et al.]253
22Oral Vaccine Production in the Edible Tissues of Transgenic Plants / Charles J. Arntzen, Hugh S. Mason263
23DNA-Based Vaccines: Extending the Technology / Stephen Albert Johnston, Kathryn F. Sykes, Michael A. Barry279
24Vaccination Against Influenza with Plasmid DNA: Cross-Strain and Homologous Protection / John J. Donnelly, Jeffrey B. Ulmer, Margaret A. Liu287
25Vaccinia Virus as a Live Vector for Expression of Immunogens / Charles Flexner, Bernard Moss297
26Attenuated Poliovirus as Live Vector / Matthias Gromeier, Hui-Hua Lu, Steffen Mueller [et al.]315
27Attenuated Salmonella as a Live Vector for Expression of Foreign Antigens331
 iExpressing Bacterial Antigens / S. N. Chatfield, Gordon Dougan331
 iiCarrying Viral Antigens / Fiorian Schodel343
 iiiSalmonella Expressing Protozoal Antigens / Myron M. Levine, James E. Galen, Marcelo B. Sztein [et al.]351
28BCG as a Recombinant Vaccine Vector / Glenn J. Fennelly, William R. Jacobs, Jr., Barry R. Bloom363
29Attenuated Vibrio cholerae as a Live Vector for Expression of Foreign Antigens / Joan R. Butterton, Stephen B. Calderwood379
30New and Improved Vaccines Against Pertussis / Erik L. Hewlett, James D. Cherry387
31New and Improved Vaccines Against Diphtheria and Tetanus / Rino Rappuoli417
32Progress in Development of New Attenuated Strains of Salmonella typhi as Live Oral Vaccines Against Typhoid Fever / Myron M. Levine, Carol O. Tacket, James E. Galen [et al.]437
33New and Improved Vaccines Against Cholera447
 iAttenuated Vibrio cholerae O1 and O139 Strains as Live Oral Cholera Vaccines / James B. Kaper, Carol O. Tacket, Myron M. Levine447
 iiOral B Subunit Killed Whole-Cell Cholera Vaccine / Jan Holmgren, Marianne Jertborn, Ann-Mari L. Svennerholm459
34New and Improved Vaccines Against Meningococcal Disease / Wendell D. Zollinger469
35Epidemiological Impact of Conjugate Vaccines on Invasive Disease Caused by Haemophilus influenzae Type b / Jay D. Wenger, Robert Booy, Paul T. Heath [et al.]489
36Conjugate Vaccines Against Streptococcus pneumoniae / David L. Klein, Ronald W. Ellis503
37Vaccine Development for Rickettsial Infections: Rocky Mountain Spotted Fever, Epidemic Typhus, and Scrub Typhus / Kimberly W. Schuenke, David H. Walker527
38New and Improved Vaccines Against Influenza / Mary Lou Clements, Ina Stephens545
39New Vaccines Against Hepatitis A / Jack T. Stapleton, Stanley M. Lemon571
40New and Improved Vaccines for Dengue, Japanese Encephalitis, and Yellow Fever Viruses / Niranjan Kanesa-thasan, Robert Putnak, Charles H. Hoke, Jr.587
41Improved Vaccines Against Rabies / Zhen Fang Fu, Bernhard Dietzschold, Stanley A. Plotkin [et al.]607
42Combination Vaccines for Routine Infant Immunization: Prospects, Progress, and Dilemmas / Carole Heilman, N. Regina Rabinovich619
43New Vaccines Against Tuberculosis / Douglas Young, Uli Fruth631
44Live Attenuated Varicella Vaccines / Michiaki Takahashi, Anne A. Gershon647
45Vaccines Against Rotavirus / Paul A. Offit, H. Fred Clark, Albert Z. Kapikian659
46Experimental HIV-1 Vaccines / Mary Lou Clements673
47Vaccines Against Respiratory Syncytial Virus and Parainfluenza Virus Type 3 / James E. Crowe, Jr., Peter L. Collins, Robert M. Chanock [et al.]711
48Herpes Simplex Vaccines / Richard J. Whitley727
49Vaccines Against Arenaviruses and Filoviruses / J. Christopher S. Clegg, Anthony Sanchez749
50Vaccines Against Papillomavirus Infections / Robert W. Tindle, Ian H. Frazer767
51Vaccines Against Streptococcus pyogenes Infections / Debra E. Bessen, Vincent A. Fischetti783
52O-Specific Polysaccharide-Protein Conjugates for Prevention of Enteric Bacterial Diseases / John B. Robbins, Rachel Schneerson, Shousun C. Szu803
53Vaccines Against Gonococcal Infection / Timothy A. Mietzner, Myron S. Cohen817
54Vaccines Against Shigella Infections843
 iEscherichia coli- or Salmonella typhi-Expressing Shigella Antigens / Thomas Larry Hale, Malabi M. Venkatesan843
 iiEngineered Attenuated Mutants of Shigella as Live Oral Vaccines / Fernando Noriega, Samuel B. Formal, Karen L. Kotloff [et al.]853
55Vaccines Against Enterotoxigenic Escherichia coli Infections865
 iOral Inactivated Vaccines Against Enterotoxigenic Escherichia coli / Ann-Mari L. Svennerholm, Christina Ahren, Marianne Jertborn865
 iiLive Oral Vaccines and Subunit (Purified Fimbriae and Toxin Subunit) Vaccines / Carol O. Tacket, Myron M. Levine875
56Vaccines Against Campylobacter jejuni / Daniel A. Scott, Shahida Baqar, Donald H. Burr [et al.]885
57Vaccines Against Lyme Disease / Robert Edelman897
58Vaccines Against Dental Caries Infection / Daniel J. Smith, Martin A. Taubman913
59Vaccines Against Klebsiella, Pseudomonas, and Septicemic E. coli Infections / Alan S. Cross, Stanley J. Cryz, Jr.931
60Vaccines Against Escherichia coli and Proteus Urinary Tract Infections / Harry L. T. Mobley945
61Vaccines Against Helicobacter pylori / Adrian Lee, Christopher Doidge963
62Vaccines for Staphylococcus aureus Infections / Ali I. Fattom, Robert B. Naso979
63Vaccines Against Malaria989
 iSynthetic Peptide Vaccines Against the Sporozoite Stage of Plasmodium / Elizabeth H. Nardin, Ruth S. Nussenzweig989
 iiVaccines Designed to Induced Protective T-Cell Responses Against Plasmodium-Infected Hepatocytes / John B. Sacci, Jr., Eileen D. Franke, Stephen L. Hoffman1009
 iiiSpf66 Vaccine Against Asexual Erythrocytic Stages of P. falciparum / Roberto Amador, Manuel E. Patarroyo1027
 ivVaccines Against Asexual Blood Stages of Plasmodium falciparum / Robin F. Anders1035
 vVaccines Against Sexual-Stage Parasites of P. falciparum: Transmission-Blocking Vaccines / David C. Kaslow1057
64Vaccines Against Leishmaniasis / Carol L. Eisenberger, Charles L. Jaffe1065
65Vaccines Against Schistosomiasis / Gilles J. Riveau, Andre Capron1081
66Antitumor Vaccines / Karl Erik Hellstrom, Ingegerd Hellstrom, Lieping Chen1095
67Vaccine Therapy / Donald S. Burke1117
68Vaccines to Prevent Pregnancy / Vernon C. Stevens, Warren R. Jones1131
69An Anti-arthropod Vaccine: TickGARD - A Vaccine to Prevent Cattle Tick Infestations / Gary S. Cobon1145
70Large-Scale Production of Live Attenuated Bacterial and Viral Vaccines / Stanley J. Cryz, Jr., Reinhard Gluck1153
71Vaccine Development: The Long Road from Initial Idea to Product Licensure / Jens-Peter Gregersen1165
72Inadvertant Nontarget Effects of Live Vaccines / Myron M. Levine, Eileen M. Barry1179
73The Role of the Food and Drug Administration in Vaccine Testing and Licensure / Bascomb F. Anthony, Ann Sutton1185
 Index1195


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