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Title Antibody Fc : linking adaptive and innate immunity / [edited by] Margaret E. Ackerman, Falk Nimmerjahn.
Imprint London ; Waltham, MA ; San Diego, CA : Elsevier/Academic Press, 2014.
Edition First edition.

Subject Immunoglobulins.
Antibody diversity.
Receptors, Fc -- immunology.
Adaptive Immunity.
Antibodies -- therapeutic use.
Immunity, Innate.
Receptors, Fc -- physiology.
Alt Name Ackerman, Margaret E.,
Nimmerjahn, Falk,
Description 1 online resource (376 pages) : illustrations (chiefly color)
Edition First edition.
Summary Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology.
Bibliography Note Includes bibliographical references and index.
Contents 1. Effector mechanisms -- 2. Effector cells -- 3. FcR -- 4. Variability of the Fc domain -- 5. Genetic associations -- 6. Evolving areas.
Note Online resource; title from resource home page (ebrary, viewed on June 17, 2014).
ISBN 9780123948182 (electronic bk.)
0123948185 (electronic bk.)
9780123948021 (hbk.)
0123948029 (hbk.)
ISBN/ISSN 9780123948021
OCLC # 855505336
Additional Format Print version: Ackerman, Margaret. Antibody Fc: Burlington : Elsevier Science, ©2013 9780123948021 (OCoLC)811206363

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