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Title Interventions for persisting ductus arteriosus in the preterm infant / M. Obladen (editor), P. Koehne (editor).
Imprint Heidelberg : Springer Medizin, 2005.

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Subject Ductus arteriosus.
Premature infants.
Ductus Arteriosus, Patent -- drug therapy.
Ductus Arteriosus, Patent -- surgery.
Infant, Premature.
Humans.
Infant.
Alt Name Obladen, M. (Michael), 1944-
Koehne, P. (Petra)
Description 1 online resource (xi, 103 pages) : illustrations
Bibliography Note Includes bibliographical references and index.
Contents Cover -- Preface -- Part I: Basics -- 1 Developmental Anatomy of the Ductus Arteriosus -- Introduction -- Embryogenesis -- Ductal Maturation -- Patent Ductus Arteriosus in Premature Infants -- Persistent Ductus Arteriosus (PDA) -- Summary -- References -- 2 Regulation of Smooth Muscle Contraction -- 3 Prostaglandin Metabolism and Effects of Inhibitors -- 4 Postnatal Circulatory Adaptation -- 5 Epidemiology of Persisting Ductus in Preterm Infants -- Congenital Anomaly or Prolonged Adaptation? -- Clinical Relevance -- Frequency Depends on Immaturity and Echocardiograph -- Individual Variability -- Conclusions -- References -- Part II: Clinical Features -- 6 Persisting Ductus Arteriosus and Respiratory Problems -- Association with Pulmonary Immaturity / Surfactant Deficiency -- Association with Pulmonary Infection / Inflammatory Response -- X-Ray Opacities -- PDA, Lung Water, and Pulmonary Hemorrhage . . 27 Lung Mechanics -- Surfactant Substitution -- Chronic Lung Disease -- Conclusions . -- References -- 7 Influence on Mesenteric Perfusion and Necrotizing Enterocolitis -- Introduction -- Mesenteric Perfusion -- Patent Ductus Arteriosus and Mesenterial Perfusion. -- Necrotizing Enterocolitis -- Patent Ductus Arteriosus and Necrotizing Enterocolitis. -- Indomethacin Intervention -- Indomethacin Versus Ibuprofen -- Conclusions -- References -- 8 Persisting Ductus Arteriosus and Intraventricular Hemorrhage -- Cerebral Perfusion -- PDA, Lung Maturity, and IVH -- Pharmacological Interventions -- Conclusions -- References -- Part III: Diagnostics -- 9 Echocardiographic Assessment -- 10 Cerebral Doppler Sonographic Measurements -- Intracranial Arteries -- Doppler Parameters -- PDA-Specific Flow Patterns -- Conclusions -- References -- Part IV: Interventions -- 11 Therapeutic Options -- Prevention of PDA -- Prophylactic Administration of Cyclooxygenase Inhibitors -- Indomethacin -- Ibuprofen -- Hamburg Ibuprofen Study -- Current Hamburg Concept of PDA Treatment -- References -- 12 Surgical Closure -- History -- Transport to the Operating Room -- Preparation for Operation in the NICU -- Perioperative Management -- Surgical Management -- Postoperative Management -- Complications -- Outcome and Complications in our Center -- Minimally Invasive Approaches -- References -- 13 Comparison of Indomethacin and Ibuprofen -- Properties of Ibuprofen -- Therapy and Prophylaxis of Patent Ductus Arteriosus -- Effects on Regional Circulation -- Pharmacokinetics . -- Conclusions -- References -- 14 Indomethacin Effects and Side Effects -- Effects -- Management of Symptomatic PDA -- Management of Asymptomatic PDA -- Prophylactic Indomethacin -- Conclusions Regarding Effects -- Side Effects -- Impairment of Renal Function -- Impairment of Cerebral Perfusion -- Abdominal Side Effects -- Interference With Blood Glucose -- Platelet Dysfunction -- Contraindications . -- Conclusions -- References . --tidtid3373.
Note Print version record.
ISBN 9783540265092
3540265090
3540245111 (alk. paper)
9783540245117 (alk. paper)
9786610337361 (electronic bk.)
6610337365 (electronic bk.)
OCLC # 209867299
Additional Format Print version: Interventions for persisting ductus arteriosus in the preterm infant. Heidelberg : Springer Medizin, 2005 3540245111 9783540245117 (OCoLC)60115873.



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