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Title Five-lipoxygenase products in asthma / edited by Jeffrey M. Drazen, Sven-Erik Dahlen, Tak H. Lee.
Imprint New York : M. Dekker, [1998]
©1998

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LOCATION CALL # STATUS MESSAGE
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Series Lung biology in health and disease ; v. 120
Lung biology in health and disease ; v. 120.
Subject Asthma -- Pathophysiology.
Leukotrienes -- Pathophysiology.
Leukotrienes -- Metabolism.
Asthma -- Chemotherapy.
Lipoxygenase Inhibitors.
Arachidonate 5-Lipoxygenase -- metabolism.
Leukotriene Antagonists.
Leukotrienes -- metabolism.
Lipoxygenase Inhibitors -- therapeutic use.
Asthma -- drug therapy.
Alt Name Dahlén, Sven-Erik.
Lee, T. H. (Tak Hong)
Drazen, Jeffrey M., 1946-
NetLibrary, Inc.
Add Title 5-lipoxygenase products in asthma.
Description 496 pages cm.
polychrome rdacc
Bibliography Note Includes bibliographical references and index.
Reproduction Electronic reproduction. Boulder, Colo. : NetLibrary, 2000. Available via World Wide Web. Access may be limited to NetLibrary affiliated libraries.
ISBN 0585270511 (electronic bk.) : $150.00
0824701674 (alk. paper)
OCLC # 45729407
Additional Format Original (DLC) 98026626 (OCoLC)39236362.
Table of Contents
 Series Introduction / Claude Lenfant 
 Preface 
 Contributors 
1Overview of the 5-Lipoxygenase Pathway / Jesper Z. Haeggstrom, Bengt Samuelsson1
25-Lipoxygenase and 5-Lipoxygenase-Activating Protein / Jilly F. Evans11
3Leukotriene C[subscript 4] Synthase: A Pivotal Enzyme in the Biosynthesis of Cysteinyl Leukotrienes / John F. Penrose, K. Frank Austen33
4Leukotriene A[subscript 4] Hydrolase / Jesper Z. Haeggstrom51
5Leukotriene Export in Human Leukocytes / Bing K. Lam77
6Pathways of Leukotriene Metabolism in Isolated Cell Models and Human Subjects / Robert C. Murphy, Pat Wheelan87
7Cell Biology of the 5-Lipoxygenase Pathway: Amplification and Generation of Leukotrienes and Lipoxins by Transcellular Biosynthesis / Timothy D. Bigby, Bruce D. Levy, Charles N. Serhan125
8Leukotriene Receptors: Incompletely Defined Targets for Treatment of Asthma and Inflammation / Sven-Erik Dahlen175
9Physiological Effects of the Leukotrienes in Humans / Neil C. Barnes, Lewis J. Smith193
10Analysis of Leukotrienes and Lipoxins / Graham W. Taylor211
11Measurement of Leukotrienes from Human Biological Fluids / Jay Y. Westcott, Ian K. Taylor245
12Cysteinyl-Leukotriene Receptor Antagonism and 5-Lipoxygenase Inhibition in Asthma / S. M. Shuaib Nasser, Tak H. Lee283
13Leukotriene Receptor Antagonism and Synthesis Inhibition in Chronic Stable Asthma / Elliot Israel, Jeffrey M. Drazen307
14Montelukast - An Antileukotriene Treatment for Asthma: Changing the Asthma-Treatment Paradigm / Beth C. Seidenberg, Theodore F. Reiss327
15Pranlukast - The First Orally Active Cysteinyl Leukotriene Receptor Antagonist Marketed for the Treatment of Asthma / Jeffrey W. Dubb, Anthony S. Rebuck347
16Zafirlukast / Catherine M. Bonuccelli, Trevor J. C. Higgins365
17Zileuton: The First Leukotriene Synthesis Inhibitor for Use in the Management of Chronic Asthma / Louise M. Dube, Linda J. Swanson, Walid M. Awni [et al.]391
18Antileukotrienes in the Management of Asthma / Paul M. O'Byrne429
 Author Index439
 Subject Index481


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