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Title Therapeutic applications of cell microencapsulation / edited by Jose Luis Pedraz, Gorka Orive.
Imprint New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, 2010.

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Series Advances in experimental medicine and biology ; v. 670
Advances in experimental medicine and biology ; v. 670.
Subject Animal cell biotechnology.
Microencapsulation.
Cells, Immobilized.
Drug Compounding -- methods.
Drug Delivery Systems -- methods.
Alt Name Pedraz, José Luis.
Orive, Gorka.
Description 1 online resource (xxi, 147 pages) : illustrations (some color).
Bibliography Note Includes bibliographical references and index.
Contents Highlights and trends in cell encapsulation / Gorka Orive and Jose Luis Pedraz -- Biomaterials in cell microencapsulation / Edorta Santos [and others] -- Development of subsieve-size capsules and application to cell therapy / Shinji Sakai and Koei Kawakami -- Regulatory considerations in application of encapsulated cell therapies / J. van Zanten and Paul de Vos -- Treatment of diabetes with encapsulated islets / Paul de Vos, Milica Spasojevic and Marijke M. Faas -- Epo delivery by genetically engineered C2C12 myoblasts immobilized in microcapsules / Ainhoa Murua [and others] -- Artificial cell microencapsulated stem cells in regenerative medicine, tissue engineering and cell therapy / Zun Chang Liu and Thomas Ming Swi Chang -- Microencapsulated choroid plexus epithelial cell transplants for repair of the brain / Christopher G. Thanos, Briannan Bintz and Dwaine F. Emerich -- Therapeutic application of cell microencapsulation in cancer / Brian Salmons and Walter H. Gunzburg -- Inorganic nanoporous membranes for immunoisolated cell-based drug delivery / Adam Mendelsohn and Tejal Desai -- Cell microencapsulation / Grace J. Lim [and others] -- Commercial applicability of cell microancapsulation : a review of intellectual property rights / Stephan M. Meier.
Summary The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire. As an illustration of the frantic pace of scientific disc- more acute in the case of scientific fields at the interface of different and seemingly distant areas of study. Amidst these, the field of cell encapsulation brings together an array of diverse disciplines such as molecular biology and biopolymers, gene therapy and inorganic membranes, stem cell biology and physicochemistry, immunology and nanotechnology. Clearly, such range of topics is too broad for any individual scientist the state-of-the-art in the field of cell encapsulation. At the core of this technology, there is an interaction of physicochemical and biological elements forming three distinct layers of complexity. First, the chemistry of the biopolymer dictates the degree of protein adsorption, vascularization, tox- ity and biocompatibility of the microcapsules. Advances in biopolymer science are providing solutions to overcome existing challenges and to improve microcapsules as delivery vehicles. Second, the choice of cells, and more precisely the plethora of in determining the immune response elicited by the host to implanted microcapsules.
Note Print version record.
ISBN 9781441957863 (electronic bk.)
1441957863 (electronic bk.)
9781441957856
1441957855
OCLC # 697197696
Additional Format Print version: Therapeutic applications of cell microencapsulation. New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, 2010 9781441957856 (DLC) 2009046493 (OCoLC)463631900



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